CAS 95633-27-5

7-azido-4-methyl-chromen-2-one

Description:

7-Azido-4-methyl-chromen-2-one, identified by its CAS number 95633-27-5, is a chemical compound belonging to the class of chromenones, which are characterized by a benzopyranone structure. This compound features an azido group (-N3) at the 7-position and a methyl group (-CH3) at the 4-position of the chromenone ring. The presence of the azido group imparts unique reactivity, making it a potential candidate for various applications in organic synthesis and medicinal chemistry, particularly in the development of bioactive compounds. The chromenone moiety is known for its diverse biological activities, including antioxidant and anti-inflammatory properties. Additionally, the compound may exhibit fluorescence, which can be advantageous in imaging applications. Its stability and solubility characteristics can vary depending on the solvent and environmental conditions, influencing its reactivity and potential uses. Overall, 7-azido-4-methyl-chromen-2-one represents a versatile scaffold for further chemical modifications and research in the field of organic and medicinal chemistry.

Formula: C₁₀H₇N₃O₂

InChI: InChI=1/C10H7N3O2/c1-6-4-10(14)15-9-5-7(12-13-11)2-3-8(6)9/h2-5H,1H3

SMILES: Cc1cc(=O)oc2cc(ccc12)N=[N+]=[NH-]

Synonyms:

• 7-Azido-4-Methylcoumarin

7-Azido-4-methylcoumarin

CAS: 95633-27-5

7-Azido-4-methylcoumarin is a fluorescent photoreactive probe for studying the substrate-binding site of human phenol sulfotransferase.

Formula: C₁₀H₇N₃O₂

Purity: 99.37%

Color and Shape: Solid

Molecular weight: 201.18

Ref: TM-T37000

7-Azido-4-methylcoumarin

CAS: 95633-27-5

Formula: C₁₀H₇N₃O₂

Purity: 98%

Molecular weight: 201.1815

Ref: IN-DA01FL2K

7-Azido-4-methylcoumarin

CAS: 95633-27-5

7-Azido-4-methylcoumarin

Purity: ≥98%

Molecular weight: 201.18g/mol

Ref: 54-BUP21063

7-Azido-4-methylcoumarin

CAS: 95633-27-5

Formula: C₁₀H₇N₃O₂

Molecular weight: 201.2

Ref: 7W-GL6932

7-Azido-4-methylcoumarin

Controlled Product

CAS: 95633-27-5

Applications 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine β-synthase (CBS), cystathionine γ-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine β-synthase (CBS) inhibitors and activators. The aromatic azide moiety is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with ?ex = 365 nm and ?em = 450 nm. It has been characterized as a novel fluorescent photoactive probe for use in photoaffinity labeling of the substrate binding site of human phenol sulfotransferase (SULT1A1 or P-PST-1)
References Chen G, et al. Protein Sci. 1999 Oct;8(10):2151-7.Collom SL el al. Arch Biochem Biophys. 2007 Mar 1;459(1):59-69

Formula: C₁₀H₇N₃O₂

Color and Shape: Neat

Molecular weight: 201.181

Ref: TR-A884803