CAS 956903-21-2

(2R,3R,11bR)-rel-9-deMe-DTBZ

Controlled Product

CAS: 956903-21-2

Applications (+/-)-9-deMe-DTBZ is a desmethyl derivative of Tetrabenzine (T284000), a dopamine depleting agent. An antidyskinetic; antipsychotic.
References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),

Formula: C₁₈H₂₇NO₃

Color and Shape: Neat

Molecular weight: 305.41

Ref: TR-D230735

(2R,3R,11Br)-rel-9-deme-dtbz

CAS: 956903-21-2

(2R,3R,11Br)-rel-9-deme-dtbz is an analog of tolvaptan that has potent anticancer properties. It acts as a kinase inhibitor and induces apoptosis in cancer cells. This compound has been shown to inhibit the activity of several kinases, including protein kinase B (AKT), mitogen-activated protein kinase (MAPK), and extracellular signal-regulated kinase (ERK). It also inhibits the growth of human tumor xenografts in Chinese hamsters. Additionally, (2R,3R,11Br)-rel-9-deme-dtbz has been found to be a promising candidate for the treatment of cancer due to its high selectivity towards cancer cells and low toxicity towards normal cells. Its potent anticancer activity makes it a valuable tool for cancer research and drug development.

Formula: C₁₈H₂₇NO₃

Purity: Min. 95%

Molecular weight: 305.4 g/mol

Ref: 3D-GNB90321