CAS 957-66-4

(3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one

Description:

The chemical substance known as (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one, with the CAS number 957-66-4, is a complex organic compound characterized by its unique bicyclic structure that incorporates both furan and benzo-furan moieties. This compound features multiple functional groups, including methyl and ethenyl substituents, which contribute to its reactivity and potential biological activity. The stereochemistry indicated by the (3aS) and (4β) designations suggests specific spatial arrangements of atoms, which can significantly influence the compound's properties and interactions. Typically, such compounds may exhibit interesting pharmacological activities, making them of interest in medicinal chemistry. Additionally, their structural complexity often leads to unique physical properties, such as solubility and melting points, which are essential for applications in various fields, including pharmaceuticals and materials science. Understanding the characteristics of this compound requires a thorough examination of its molecular interactions and potential applications.

Formula: C₁₂H₂₀O₂

Synonyms:

• (3aS)-4β-Vinyl-3a,4,5,8bβ-tetrahydro-4,8-dimethyl-3-methylenebenzo[1,2-b:3,4-b']difuran-2(3H)-one
• Reaxys ID: 5276986
• 3,4-b']difuran-2(3H)-one
• Isolinderalactone
• (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one
• (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b
• (3aS)-4,8-Dimethyl-3-methylene-4β-ethenyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b]difuran-2(3H)-one
• Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 4-ethenyl-3a,4,5,8b-tetrahydro-4,8-dimethyl-3-methylene-, (3aS,4R,8bR)-
• (3aS,4R,8bR)-4,8-Dimethyl-3-methylene-4-vinyl-3a,4,5,8b-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one
• Survivin,VEGFR,Isolinderalactone,Vascular endothelial growth factor receptor,Inhibitor,IAP,Bcl-2 Family,inhibit

Isolinderalactone

CAS: 957-66-4

Formula: C₁₅H₁₆O₃

Purity: 98%

Molecular weight: 244.2857

Ref: IN-DA01DDEH

Isolinderalactone

CAS: 957-66-4

Isolinderalactone

Purity: ≥98%

Molecular weight: 244.29g/mol

Ref: 54-BUP04881

Isolinderalactone

CAS: 957-66-4

Formula: C₁₅H₁₆O₃

Purity: 95%~99%

Molecular weight: 244.29

Ref: BP-BP4965

Isolinderalactone

CAS: 957-66-4

Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.

Formula: C₁₅H₁₆O₃

Purity: 99.62%

Color and Shape: Solid

Molecular weight: 244.29

Ref: TM-T8213

Isolinderalactone

CAS: 957-66-4

Isolinderalactone is a sesquiterpene lactone that has inhibitory properties against bowel disease and cancer. It also inhibits the apoptosis pathway in cells, leading to cell lysis. Isolinderalactone has been shown to have anti-inflammatory, antioxidant, and immunomodulatory effects. It can be used for the treatment of bowel disease, cancer, and other diseases that are caused by oxidative stress. Isolinderalactone may also be useful for the prevention of heart failure or stroke. This drug binds to an allosteric site on mitochondrial membranes and induces cell death through caspase-independent pathways. Isolinderalactone may also be used as a natural drug due to its molecular docking analysis with tubulin polymerization factor 1 (WST-1).

Formula: C₁₅H₁₆O₃

Purity: Min. 95%

Molecular weight: 244.29 g/mol

Ref: 3D-AAA95766