CAS 959122-11-3

(1R,2R)-2-[[4′-[[(Phenylamino)carbonyl]amino][1,1′-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid

Description:

The chemical substance known as (1R,2R)-2-[[4′-[[(Phenylamino)carbonyl]amino][1,1′-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid, with the CAS number 959122-11-3, is a complex organic compound characterized by its multi-functional groups and stereochemistry. It features a cyclopentane ring, which contributes to its three-dimensional structure, and contains multiple carbonyl groups that enhance its reactivity and potential for forming hydrogen bonds. The presence of a phenylamino group indicates potential interactions with biological targets, making it of interest in medicinal chemistry. The specific stereochemistry (1R,2R) suggests that it may exhibit unique biological activity or pharmacokinetic properties due to its spatial arrangement. This compound may be investigated for its potential therapeutic applications, particularly in the context of drug design, where the balance of lipophilicity and hydrophilicity, as well as the ability to interact with specific biological receptors, are crucial for efficacy. Overall, its structural complexity and functional diversity make it a subject of interest in chemical and pharmaceutical research.

Formula: C₂₆H₂₄N₂O₄

InChI: InChI=1S/C26H24N2O4/c29-24(22-7-4-8-23(22)25(30)31)19-11-9-17(10-12-19)18-13-15-21(16-14-18)28-26(32)27-20-5-2-1-3-6-20/h1-3,5-6,9-16,22-23H,4,7-8H2,(H,30,31)(H2,27,28,32)/t22-,23-/m1/s1

InChI key: InChIKey=BOZRFEQDOFSZBV-DHIUTWEWSA-N

SMILES: C(=O)([C@H]1[C@H](C(O)=O)CCC1)C2=CC=C(C=C2)C3=CC=C(NC(NC4=CC=CC=C4)=O)C=C3

Synonyms:

• (1R,2R)-2-[[4′-[[(Phenylamino)carbonyl]amino][1,1′-biphenyl]-4-yl]carbonyl]cyclopentanecarboxylic acid
• A 922500
• Cyclopentanecarboxylic acid, 2-[[4'-[[(phenylamino)carbonyl]amino][1,1'-biphenyl]-4-yl]carbonyl]-, (1R,2R)-
• DGAT-1 INHIBITOR 4A; A-922500; A922500
• DGAT-1 Inhibitor 4a
• (1R,2R)-2-(4'-(3-phenylureido)biphenylcarbonyl)cyclopentanecarboxylic acid
• enylureido)biphenyl(1R,2R)-2-(4'-(3-phcarbonyl)cyclopentanecarboxylic acid
• (1R,2R)-2-(4,-(3-phenylureido)-[1,1,-biphenyl]-4-carbonyl)cyclopentanecarboxylic acid
• DGAT-1 Inhibitor, A 922500 - CAS 959122-11-3 - Calbiochem
• CS-121
• DGAT-1 Inhibitor, A 922500
• DGAT-1 inhibitor
• A922500
• Diacyl glycerolacyltransferase 1 inhibitor
• DGAT-1 inhibitor USP/EP/BP

A 922500

CAS: 959122-11-3

Formula: C₂₆H₂₄N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 428.4798

Ref: IN-DA019FY5

A 922500

CAS: 959122-11-3

A 922500

Purity: ≥95%

Molecular weight: 428.48g/mol

Ref: 54-BUP09280

(1R,2R)-2-(4-(3-Phenylureido)-[1,1-Biphenyl]-4-Carbonyl)Cyclopentanecarboxylic Acid

CAS: 959122-11-3

(1R,2R)-2-(4-(3-Phenylureido)-[1,1-Biphenyl]-4-Carbonyl)Cyclopentanecarboxylic Acid

Purity: 98%

Molecular weight: 428.48g/mol

Ref: 54-OR1023230

A 922500

CAS: 959122-11-3

Formula: C₂₆H₂₄N₂O₄

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 428.49

Ref: 3B-D5994

A 922500

CAS: 959122-11-3

A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1, good selectivity over related acyltransferases, hERG, and a panel of anti-targets.

Formula: C₂₆H₂₄N₂O₄

Purity: 97.34% - 97.66%

Color and Shape: Solid

Molecular weight: 428.48

Ref: TM-T6365

A 922500

CAS: 959122-11-3

Inhibits human and mouse diacylglycerol O-acyltransferase 1 (DGAT-1) with IC50 values of 9 and 22 nM, respectively. Selective for DGAT-1 over DGAT-2 (IC50 = 53 µM), acyl coenzyme A transferase (IC50 = 296 µM) and other acyltransferases. Reduces plasma and liver triglycerides, FFA, chylomicron secretion and increases HDL cholesterol in vivo.

Formula: C₂₆H₂₄N₂O₄

Purity: Min. 95%

Molecular weight: 428.48 g/mol

Ref: 3D-FA64929

A 922500

Controlled Product

CAS: 959122-11-3

Formula: C₂₆H₂₄N₂O₄

Color and Shape: Neat

Molecular weight: 428.48

Ref: TR-A965370