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CAS 959996-48-6

:

(2-bromo-5-fluorophenyl)boronic acid

Description:
(2-Bromo-5-fluorophenyl)boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that is substituted with both bromine and fluorine atoms. This compound typically exhibits a white to off-white crystalline solid form and is soluble in polar solvents such as water and alcohols, owing to the boronic acid group, which can engage in hydrogen bonding. The presence of the bromine and fluorine substituents can influence its reactivity and stability, making it useful in various chemical reactions, particularly in Suzuki coupling reactions for the formation of carbon-carbon bonds. Additionally, boronic acids are known for their ability to form reversible complexes with diols, which can be exploited in sensor applications and drug design. The compound's unique electronic properties, derived from the halogen substituents, may also enhance its utility in medicinal chemistry and materials science. Overall, (2-bromo-5-fluorophenyl)boronic acid serves as a valuable intermediate in organic synthesis and pharmaceutical development.
Formula:C6H5BBrFO2
InChI:InChI=1/C6H5BBrFO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3,10-11H
SMILES:c1cc(c(cc1F)B(O)O)Br
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90
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95
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