CAS 96-72-0

2-Chloro-5-nitrobenzenesulfonamide

Description:

2-Chloro-5-nitrobenzenesulfonamide is an organic compound characterized by its sulfonamide functional group, which is attached to a benzene ring that also features a chlorine atom and a nitro group. This compound is typically a solid at room temperature and is known for its crystalline structure. It is soluble in polar solvents, such as water and alcohols, but may have limited solubility in non-polar solvents. The presence of the nitro group contributes to its electron-withdrawing properties, which can influence its reactivity and interactions in chemical reactions. 2-Chloro-5-nitrobenzenesulfonamide is often utilized in pharmaceutical applications and as an intermediate in organic synthesis. It may exhibit antibacterial properties due to the sulfonamide moiety, which is a common feature in many antimicrobial agents. Safety precautions should be taken when handling this compound, as it may pose health risks, including potential toxicity and irritant effects. Proper storage and disposal methods are essential to mitigate any environmental impact.

Formula: C₆H₅ClN₂O₄S

InChI: InChI=1S/C6H5ClN2O4S/c7-5-2-1-4(9(10)11)3-6(5)14(8,12)13/h1-3H,(H2,8,12,13)

InChI key: InChIKey=ZAJALNCZCSSGJC-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C1=CC(N(=O)=O)=CC=C1Cl

Synonyms:

• 2-Chloro-5-Nitrobenzene Sulfonamide
• 2-Chloro-5-Nitrobenzenesulfonamide
• 2-Chloro-5-nitrobenzene-1-sulfonamide
• Benzenesulfonamide, 2-chloro-5-nitro-
• NSC 105711

2-Chloro-5-nitrobenzenesulfonamide

CAS: 96-72-0

Formula: C₆H₅ClN₂O₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 236.6329

Ref: IN-DA006OZI

2-Chloro-5-nitrobenzenesulfonamide

CAS: 96-72-0

2-Chloro-5-nitrobenzenesulfonamide

Purity: 98%

Molecular weight: 236.63g/mol

Ref: 54-OR75559

2-Chloro-5-nitrobenzene sulfonamide

CAS: 96-72-0

2-Chloro-5-nitrobenzene sulfonamide (2CNS) is a glycol ether that has been shown to inhibit the activity of carbonic anhydrase. It has been shown to be a competitive inhibitor of the enzyme, and can be used as a lead compound for developing new drugs. 2CNS has been shown to inhibit an anhydrase that is found in bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus. This inhibition causes increased levels of hydrogen ions in the bacterial environment, which leads to the acidification of their surroundings. 2CNS also inhibits chloride ion uptake in these bacteria.
2CNS's pharmacophore includes two aromatic hydrocarbon rings with at least one hydrogen bond acceptor group on each ring. This pharmacophore is responsible for its inhibition of carbonic anhydrase and chloride ion binding site.

Formula: C₆H₅ClN₂O₄S

Purity: Min. 97 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 236.63 g/mol

Ref: 3D-FC00928

2-Chloro-5-nitrobenzenesulfonamide

CAS: 96-72-0

Formula: C₆H₅ClN₂O₄S

Purity: 98%

Molecular weight: 236.63

Ref: 10-F049180

2-Chloro-5-nitrobenzenesulfonamide

Controlled Product

CAS: 96-72-0

Applications 2-Chloro-5-nitrobenzenesulfonamide (cas# 96-72-0) is a compound useful in organic synthesis.

Formula: C₆H₅ClN₂O₄S

Color and Shape: Neat

Molecular weight: 236.63

Ref: TR-C373880