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CAS 96036-02-1

:

protected meropenem

Description:
Protected meropenem, identified by the CAS number 96036-02-1, is a synthetic beta-lactam antibiotic that belongs to the carbapenem class. It is characterized by its broad-spectrum antibacterial activity, particularly against Gram-positive and Gram-negative bacteria, including those resistant to other antibiotics. The "protected" designation indicates that certain functional groups in the molecule are modified to enhance stability or bioavailability, which can be crucial for its pharmacological properties. Meropenem itself is known for its ability to inhibit bacterial cell wall synthesis, leading to cell lysis and death. The compound typically exhibits good solubility in water and is often administered via injection due to its instability in acidic environments. Its use is primarily in treating severe infections, including those caused by multidrug-resistant organisms. However, the specific characteristics of protected meropenem may vary depending on the nature of the protective groups and the formulation used. Overall, it represents a significant advancement in antibiotic therapy, particularly in the context of increasing antibiotic resistance.
Formula:C32H35N5O11S
InChI:InChI=1/C32H35N5O11S/c1-17-26-25(18(2)38)30(40)35(26)27(31(41)47-15-19-5-9-21(10-6-19)36(43)44)28(17)49-23-13-24(29(39)33(3)4)34(14-23)32(42)48-16-20-7-11-22(12-8-20)37(45)46/h5-12,17-18,23-26,38H,13-16H2,1-4H3/t17-,18-,23?,24+,25-,26-/m1/s1
Synonyms:
  • 4-Nitrobenzyl (5S,6S)-3-[((3S,5S)-5-[(Dimethylamino)Carbonyl]-1-{[(4-Nitrobenzyl)Oxy]Carbonyl}Pyrrolidinyl)Sulfanyl]-6-[(1R)-1-Hydroxyethyl]-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylate
  • Meropenem & Intermediates Protected Meropenem P-NITROBENZYL(4R,5S,6S)-3-[(3S,5S)-(5-DIMETHYLAMINOCARBONYL-1-P-NITROBENZYLOXYCARBONYL)-PYRROLIDIN-3-YLSULFANYL]-6-((R)-1-HYDROXY-ETHYL)-4-METHYL-7-OXO-1-AZA-BICYCLO[3.2.0]HEPT-2ENE-4-CARBOXYLATE
  • Intermediate Of Meropenem
  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • 3-(((3S,5S)-5-((dimet hylamino)carbonyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-(4R,5S,6S)-1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • 3-((5-((dimethylamino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-(4R-(3(S*,5S*)
  • 4-alpha,5-beta,6-beta(R*)))
  • Antibiotic SM 7338
  • Brn 6940582
  • Ici 194660
  • See more synonyms
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