CAS 96036-03-2

Meropenem

Description:

Meropenem is a broad-spectrum, beta-lactam antibiotic belonging to the carbapenem class, primarily used to treat severe bacterial infections. It exhibits a wide range of activity against both Gram-positive and Gram-negative bacteria, including many strains resistant to other antibiotics. Meropenem works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is typically administered intravenously due to its instability in acidic environments, which limits oral bioavailability. The compound is characterized by its high resistance to hydrolysis by most beta-lactamases, making it effective against a variety of resistant pathogens. Meropenem is often used in hospital settings for infections such as meningitis, pneumonia, and intra-abdominal infections. Its pharmacokinetics include rapid distribution in body tissues and fluids, with renal excretion being the primary route of elimination. Common side effects may include gastrointestinal disturbances, headache, and potential allergic reactions. Overall, meropenem is a critical agent in the arsenal against multidrug-resistant bacterial infections.

Formula: C₁₇H₂₅N₃O₅S

InChI: InChI=1/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)

InChI key: InChIKey=DMJNNHOOLUXYBV-PQTSNVLCSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](C(N(C)C)=O)NC3)[H]

Synonyms:

• (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimeth-ylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• 3-{[5-(Dimethylcarbamoyl)Pyrrolidin-3-Yl]Sulfanyl}-6-(1-Hydroxyethyl)-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
• Antibiotic SM 7338
• Ici 194660
• Mepem
• Meronem
• Meropen
• Meropenem anhydrous
• Meropenemum [INN-Latin]
• Meroxan
• Merrem
• Merrem IV
• Monan
• Sm 7338
• Meropenem
• )-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-,(4r-(3(s*,5s*),4-al
• STERILE MEROPENEM
• (4r,5s,6s)-3-[[(3s,5s)-5-dimethylcarbamoylpyrrolidin-3-
• MERONEM MEROPEN MEROPENEM MERREM
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-(9CI)
• (4r,5s,6s)-3-[[(3s,5s)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• MEROPENEM FOR INJECTION
• MEROPENAM
• MEROPENEM(PATENTED)
• Meropenemanhydrous
• MEROPENEM, USP STANDARD
• 5-beta,6-beta(r*)))-ph
• ici194660
• MEROPENEM, USP
• antibioticsm7338

Meropenem Trihydrate

CAS: 119478-56-7, 96036-03-2

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 437.51

Ref: 3B-M2279

(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS: 96036-03-2

Formula: C₁₇H₂₅N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 383.4625

Ref: IN-DA0038IK

Meropenem

CAS: 96036-03-2

Meropenem (SM 7338), a broad-spectrum IV antibiotic, treats severe infections but may cause mild liver enzyme elevations or rare cholestatic injury.

Formula: C₁₇H₂₅N₃O₅S

Purity: 99.66%

Color and Shape: White Or Almost White Powder Complies

Molecular weight: 383.46

Ref: TM-T0224

Meropenem

CAS: 96036-03-2

Meropenem

Purity: ≥95%

Molecular weight: 383.46g/mol

Ref: 54-BUP14836

Meropenem

CAS: 96036-03-2

Formula: C₁₇H₂₅N₃O₅S

Molecular weight: 383.46

Ref: 4Z-M-125001

Meropenem

CAS: 96036-03-2

Inhibitor of cell-wall synthesis; carbapenem class

Formula: C₁₇H₂₅N₃O₅S

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 383.46 g/mol

Ref: 3D-AM32026

Meropenem Open Chain Sodium Salt

Controlled Product

CAS: 96036-03-2

Formula: C₁₇H₂₆N₃NaO₆S

Color and Shape: Neat

Molecular weight: 423.46

Ref: TR-M225720