CAS 96036-03-2: Meropenem

Description: Meropenem is a broad-spectrum, beta-lactam antibiotic belonging to the carbapenem class, primarily used to treat severe bacterial infections. It exhibits a wide range of activity against both Gram-positive and Gram-negative bacteria, including many strains resistant to other antibiotics. Meropenem works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is typically administered intravenously due to its instability in acidic environments, which limits oral bioavailability. The compound is characterized by its high resistance to hydrolysis by most beta-lactamases, making it effective against a variety of resistant pathogens. Meropenem is often used in hospital settings for infections such as meningitis, pneumonia, and intra-abdominal infections. Its pharmacokinetics include rapid distribution in body tissues and fluids, with renal excretion being the primary route of elimination. Common side effects may include gastrointestinal disturbances, headache, and potential allergic reactions. Overall, meropenem is a critical agent in the arsenal against multidrug-resistant bacterial infections.

Formula: C₁₇H₂₅N₃O₅S

InChI: InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1

InChI key: InChIKey=DMJNNHOOLUXYBV-PQTSNVLCSA-N

SMILES: O=C(O)C1=C(SC2CNC(C(=O)N(C)C)C2)C(C)C3N1C(=O)C3C(O)C

Synonyms:

• (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimeth-ylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• 3-{[5-(Dimethylcarbamoyl)Pyrrolidin-3-Yl]Sulfanyl}-6-(1-Hydroxyethyl)-4-Methyl-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
• Antibiotic SM 7338
• Ici 194660
• Mepem
• Meronem
• Meropen
• Meropenem anhydrous
• Meropenemum [INN-Latin]
• Meroxan
• Merrem
• Merrem IV
• Monan
• Sm 7338
• Meropenem

Meropenem Trihydrate

CAS: 119478-56-7 96036-03-2

• Formula: C₁₇H₂₅N₃O₅S·3H₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 437.51

(4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS: 96036-03-2

• Formula: C₁₇H₂₅N₃O₅S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 383.4625

Meropenem

CAS: 96036-03-2

Meropenem (SM 7338), a broad-spectrum IV antibiotic, treats severe infections but may cause mild liver …

• Formula: C₁₇H₂₅N₃O₅S
• Purity: 96.62% - 99.02%
• Color and Shape: White Or Almost White Powder Complies
• Molecular weight: 383.46

Meropenem

CAS: 96036-03-2

• Purity: ≥95%
• Molecular weight: 383.46g/mol

Meropenem

CAS: 96036-03-2

• Formula: C₁₇H₂₅N₃O₅S
• Molecular weight: 383.46

Meropenem

CAS: 96036-03-2

Inhibitor of cell-wall synthesis; carbapenem class

• Formula: C₁₇H₂₅N₃O₅S
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 383.46 g/mol

Meropenem Open Chain Sodium Salt

CAS: 96036-03-2

• Formula: C₁₇H₂₆N₃NaO₆S
• Color and Shape: Neat
• Molecular weight: 423.46