CAS 960404-48-2

(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate

Description:

(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate, with CAS number 960404-48-2, is a complex organic compound characterized by its specific stereochemistry and functional groups. This substance features a glucitol backbone, which is a sugar alcohol, indicating potential solubility in water and biological relevance. The presence of a chloro group and an ethoxyphenyl moiety suggests that it may exhibit unique electronic properties and potential interactions with biological targets. The monohydrate form indicates that it contains one molecule of water per formula unit, which can influence its stability, solubility, and crystallization behavior. Such compounds are often studied for their pharmacological properties, and their structural complexity may contribute to diverse biological activities. Overall, the characteristics of this compound make it a subject of interest in medicinal chemistry and drug development, particularly in the context of designing therapeutics with specific action mechanisms.

Formula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

InChI: InChI=1S/C21H25ClO6.C3H8O2.H2O/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21;1-3(5)2-4;/h3-8,10,17-21,23-26H,2,9,11H2,1H3;3-5H,2H2,1H3;1H2/t17-,18-,19+,20-,21+;3-;/m10./s1

InChI key: InChIKey=GOADIQFWSVMMRJ-UPGAGZFNSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2.[C@@H](CO)(C)O.O

Synonyms:

• (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-<span class="text-smallcaps">D</span>-glucitol (S)-propane-1,2-diol (1:1) monohydrate
• <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate
• <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1)
• Dapagliflozin (S)-propylene glycol hydrate
• Dapagliflozin Propylene Glycolate Hydrate
• Edistride
• Farxiga
• Forxiga
• D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate
• D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1)
• (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate

DAPAGLIFLOZIN PROPYLENE GLYCOL MONOHYDRATE CRS

CAS: 960404-48-2

DAPAGLIFLOZIN PROPYLENE GLYCOL MONOHYDRATE CRS

Ref: 41-Y0002487

Dapagliflozin Propanediol

CAS: 960404-48-2

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Color and Shape: White Off-White Powder

Molecular weight: 502.19696

Ref: 45-1163253

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1)

CAS: 960404-48-2

Formula: C₂₄H₃₅ClO₉

Purity: 99%

Color and Shape: Solid

Molecular weight: 502.9823

Ref: IN-DA00IMNP

Dapagliflozin propanediol monohydrate

CAS: 960404-48-2

Formula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Purity: ≥ 98.0%

Color and Shape: White to yellow or beige powder or solid

Molecular weight: 502.98

Ref: 7W-GP6243

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

CAS: 960404-48-2

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

Purity: ≥98%

Molecular weight: 502.98g/mol

Ref: 54-BUP13707

Dapagliflozin Propanediol Hydrate

CAS: 960404-48-2

Dapagliflozin Propanediol Hydrate

Purity: 99%

Molecular weight: 502.98g/mol

Ref: 54-OR1029987

Dapagliflozin (2S)-1,2-Propanediol Monohydrate

CAS: 960404-48-2

Formula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Color and Shape: Neat

Molecular weight: 502.98

Ref: 86-MM3611.00

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

CAS: 960404-48-2

Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-

Formula: C₂₄H₃₅ClO₉

Purity: 99.88% - 99.94%

Color and Shape: Solid

Molecular weight: 502.98

Ref: TM-T4460

(2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL COMPOUND WITH (S)-PROPANE-1,2-DIOL (1:1) HYDRATE

CAS: 960404-48-2

Purity: 95%

Molecular weight: 502.989990234375

Ref: 10-F796757

Dapagliflozin Propanediol Hydrate

CAS: 960404-48-2

Formula: C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O

Color and Shape: Neat

Molecular weight: 502.98

Ref: TR-D185398

Dapagliflozin propanediol monohydrate

CAS: 960404-48-2

Dapagliflozin is an oral antidiabetic drug that acts by inhibiting the SGLT2 enzyme. The SGLT2 enzyme is responsible for reabsorbing glucose from the kidney, so by inhibiting this enzyme, glucose will be excreted in the urine and blood glucose levels will decrease. Dapagliflozin also has a low bioavailability in vivo, which can be improved by administration with food. This drug has been shown to have a longer elimination half-life than canagliflozin and empagliflozin. Dapagliflozin has been shown to have a higher potency than metformin hydrochloride in vitro.

Formula: C₂₄H₃₅ClO₉

Purity: (Hplc) Min. 99.0%

Color and Shape: Powder

Molecular weight: 502.98 g/mol

Ref: 3D-MD45346

Dapagliflozin propanediol monohydrate - Bio-X ™

CAS: 960404-48-2

Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. It inhibits glucose reabsorption in the proximal tubule of the nephron and results in glycosuria, which helps to improve glycaemic control. Also, Dapagliflozin is used to lower the risk of sustained eGFR decline, end-stage renal disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease who are at risk of progression.

Formula: C₂₁H₂₅ClO₆•C₃H₈O₂•H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 502.98 g/mol

Ref: 3D-BD300147