CAS 963-39-3
:Demoxepam
Description:
Demoxepam is a benzodiazepine derivative known for its anxiolytic and sedative properties. It is characterized by its ability to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased neuronal inhibition. This mechanism contributes to its therapeutic effects, which include the treatment of anxiety disorders and insomnia. Demoxepam is typically administered orally and has a relatively long half-life, which can result in prolonged effects. The substance is generally well-tolerated, but like other benzodiazepines, it may lead to dependence and withdrawal symptoms with prolonged use. Common side effects can include drowsiness, dizziness, and cognitive impairment. Due to its potential for abuse and dependence, demoxepam is classified as a controlled substance in many jurisdictions. It is important for users to follow medical guidance when using this medication to mitigate risks associated with its use.
Formula:C15H11ClN2O2
InChI:InChI=1S/C15H11ClN2O2/c16-11-6-7-13-12(8-11)15(10-4-2-1-3-5-10)18(20)9-14(19)17-13/h1-8H,9H2,(H,17,19)
InChI key:InChIKey=GGRWZBVSUZZMKS-UHFFFAOYSA-N
SMILES:O=N1=C(C=2C(NC(=O)C1)=CC=C(Cl)C2)C3=CC=CC=C3
Synonyms:- 1,3-Dihydro-7-Chloro-5-Phenyl-2H-1,4-Benzodiazepin-2-One4-Oxide
- 1,3-Dihydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-, 4-oxide
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-, 4-oxide
- 4-Benzodiazepin-2-One,1,3-Dihydro-7-Chloro-5-Phenyl-2H-4-Oxide
- 4-Benzodiazepin-2-One,7-Chloro-1,3-Dihydro-5-Phenyl-2H-4-Oxide
- 5-Phenyl-7-chloro-3H-1,4-benzodiazepin-2(1H)-one 4-oxide
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
- 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one-4-oxid
- 7-Chloro-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 4-oxide
- 7-chloro-4-hydroxy-5-phenyl-3,4-dihydro-2H-1,4-benzodiazepin-2-one
- 7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-oxide
- Chlordiazepoxide lactam
- Demoxepam
- NSC 169898
- NSC 46007
- NSC 46077
- See more synonyms
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Found 11 products.
Chlordiazepoxide Related Compound A (7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-Oxide)
CAS:Antidepressants, tranquilizers and other psychotherapeutic agents, nesoiFormula:C15H11ClN2O2Color and Shape:White PowderMolecular weight:286.050917-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-Oxide (Demoxepam)
CAS:Controlled ProductFormula:C15H11ClN2O2Color and Shape:NeatMolecular weight:286.71Demoxepam
CAS:Controlled Product<p>Applications A major metabolite of Chlordiazepoxide (C327050). A benzodiapine derivative with anticonvulsant properties.<br>References Coutinho, C.B. et al.: Biochem. Pharmacol., 18, 303 (1969); Robichaud, R.C. et al.: Arch. Int. Pharmacol. Ther., 211, 165 (1974);<br></p>Formula:C15H11ClN2O2Color and Shape:WhiteMolecular weight:286.71Demoxepam (1 mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C15H11ClN2O2Color and Shape:Single SolutionMolecular weight:286.71Demoxepam
CAS:Controlled Product<p>Demoxepam is a benzodiazepine drug that is used in the treatment of chronic pain. It has been shown to be more effective than lorazepam and diazepam in animal studies. Demoxepam is administered orally, with a half-life of 12 hours. This drug binds to chlordiazepoxide receptors on the GABA receptor complex, which leads to an increase in chloride influx into cells, causing hyperpolarization and decreased neuronal excitability. Demoxepam also inhibits the enzyme hydrolase (which breaks down other drugs) and can cause drug interactions by inhibiting the metabolism of other drugs, such as HIV protease inhibitors.</p>Formula:C15H11ClN2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:286.71 g/mol
