CAS 96426-21-0

gly-arg-gly-asp-ser

Description:

The chemical substance known as "gly-arg-gly-asp-ser," with the CAS number 96426-21-0, is a peptide composed of four amino acids: glycine (Gly), arginine (Arg), aspartic acid (Asp), and serine (Ser). This peptide is notable for its role in biological processes, particularly in cell adhesion and signaling. The sequence of amino acids contributes to its structural and functional properties, making it relevant in various biochemical applications, including drug development and tissue engineering. Gly-arg-gly-asp-ser may interact with specific receptors or proteins, influencing cellular behavior and responses. Its relatively small size allows for ease of synthesis and modification, which is advantageous in research and therapeutic contexts. Additionally, the presence of charged and polar side chains in the amino acids can affect solubility and interaction with other biomolecules. Overall, this peptide serves as a valuable model for studying peptide interactions and functions in biological systems.

Formula: C₁₇H₃₀N₈O₉

InChI: InChI=1/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1

SMILES: C(C[C@@H](C(=NCC(=N[C@@H](CC(=O)O)C(=N[C@@H](CO)C(=O)O)O)O)O)N=C(CN)O)CNC(=N)N

Synonyms:

• H-Gly-Arg-Gly-Asp-Ser-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-serine

H-Gly-Arg-Gly-Asp-Ser-OH

CAS: 96426-21-0

GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation.

Formula: C₁₇H₃₀N₈O₉

Purity: 96.7%

Color and Shape: White Lyophilisate

Molecular weight: 490.47

Ref: 01-4008998

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Formula: C₁₇H₃₀N₈O₉

Purity: 98%

Molecular weight: 490.4683

Ref: IN-DA019FVU

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.

Formula: C₁₇H₃₀N₈O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 490.47

Ref: TM-TP1459

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Formula: C₁₇H₃₀N₈O₉

Molecular weight: 490.47

Ref: 7W-GL3717

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

Formula: C₁₇H₃₀N₈O₉CH₃COOHH₂O

Purity: Min. 95%

Molecular weight: 490.47 g/mol

Ref: 3D-PFA-4189

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials. This product is available as a 0.5mg vial.

Formula: C₁₇H₃₀N₈O₉

Purity: Min. 95%

Molecular weight: 490.47 g/mol

Ref: 3D-PFA-4189-V

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt

CAS: 96426-21-0

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt is a synthetic peptide that is designed to bind to the nuclear factor kappa B (NFκB) and inhibit its activation. NFκB is a transcription factor that regulates gene expression in response to various stimuli, including proinflammatory cytokines, oxidants, and electrophilic compounds. H-Gly-Arg-Gly-Asp-Ser-OH TFA salt has been shown to inhibit NFκB activation in a model system. This molecule also inhibits axonal growth and pluripotent cells differentiation, which may be due to its suppression of the signal peptide. The rate constant for this drug has been measured using polymer compositions and biocompatible polymers.

Formula: C₁₇H₃₀N₈O₉(freebase)

Purity: Min. 95%

Molecular weight: 490.47 g/mol

Ref: 3D-FG108418