Bacithrocin D is a polypeptide antibiotic that is part of the bacitracin family, primarily produced by the bacterium Bacillus subtilis. It exhibits antibacterial properties, particularly against Gram-positive bacteria, making it useful in clinical and agricultural applications. The structure of Bacithrocin D consists of a cyclic peptide with a unique amino acid composition, contributing to its mechanism of action, which involves inhibiting bacterial cell wall synthesis. This antibiotic is often utilized in topical formulations due to its effectiveness against skin infections. Bacithrocin D is known for its low toxicity in humans, which enhances its safety profile for topical use. However, like many antibiotics, there is a potential for resistance development, necessitating careful use. Its stability and solubility characteristics make it suitable for various formulations, although it may require specific storage conditions to maintain its efficacy. Overall, Bacithrocin D represents an important tool in the fight against bacterial infections, particularly in settings where Gram-positive pathogens are prevalent.

Bacithrocin D

96440-64-1: Bacithrocin D is a polypeptide antibiotic that is part of the bacitracin family, primarily produced by the bacterium Bacillus subtilis. It exhibits antibacterial properties, particularly against Gram-positive bacteria, making it useful in clinical and agricultural applications. The structure of Bacithrocin D consists of a cyclic peptide with a unique amino acid composition, contributing to its mechanism of action, which involves inhibiting bacterial cell wall synthesis. This antibiotic is often utilized in topical formulations due to its effectiveness against skin infections. Bacithrocin D is known for its low toxicity in humans, which enhances its safety profile for topical use. However, like many antibiotics, there is a potential for resistance development, necessitating careful use. Its stability and solubility characteristics make it suitable for various formulations, although it may require specific storage conditions to maintain its efficacy. Overall, Bacithrocin D represents an important tool in the fight against bacterial infections, particularly in settings where Gram-positive pathogens are prevalent.

<p>Bacithrocin D (Thiolstatin D) inhibits various proteases and has the capability to prolong clotting time. It exhibits IC50 values of 124, 9, 0.85, and 0.01 μM against thrombin, factor Xa, trypsin, and papain, respectively.</p>

CAS 96440-64-1

Bacithrocin D

Bacithrocin D

Ref: TM-TN10133