CAS 96497-67-5
:Rodorubicin
Description:
Rodorubicin, also known as 4'-O-demethoxydaunorubicin, is an anthracycline antibiotic with the CAS number 96497-67-5. It is primarily used in cancer therapy, particularly for treating various types of leukemia and solid tumors. The compound exhibits potent antitumor activity by intercalating into DNA, thereby inhibiting DNA and RNA synthesis, which ultimately leads to cell death. Rodorubicin is characterized by its red color, which is typical of many anthracyclines, and it has a complex polycyclic structure that contributes to its biological activity. The drug is administered intravenously and is known for its cardiotoxicity, a common side effect associated with anthracycline derivatives. Its pharmacokinetics involve metabolism primarily in the liver, with excretion occurring through the bile. Due to its efficacy and side effects, careful monitoring is essential during treatment. Overall, Rodorubicin represents a significant therapeutic agent in oncology, with ongoing research aimed at optimizing its use and minimizing adverse effects.
Formula:C48H64N2O17
InChI:InChI=1/C48H64N2O17/c1-10-48(58)18-30(64-31-15-25(50(8)9)44(21(4)60-31)65-33-17-28-45(22(5)61-33)67-47-29(63-28)16-27(52)19(2)62-47)35-38(46(48)66-32-14-24(49(6)7)39(53)20(3)59-32)43(57)36-37(42(35)56)41(55)34-23(40(36)54)12-11-13-26(34)51/h11-13,19-22,24-25,28-33,39,44-47,51,53,56-58H,10,14-18H2,1-9H3/t19-,20-,21-,22-,24-,25-,28-,29-,30-,31-,32-,33-,39+,44+,45+,46+,47-,48+/m0/s1
Synonyms:- (1S,3R,4R)-3-Ethyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-1-naphthacenyl O-3,6-dideoxy-alpha-L-erythro-hexopyranos-4-ulosyl-(1-4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranoside, 2',3'-anhydride
- Rodorubicina [Spanish]
- Rodorubicine
- Rodorubicin [INN]
- Rodorubicinum
- (1S,3R,4R)-3-Ethyl-1,2,3,4,6,11-hexahydro-3,5,10,12-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-1-naphthacenyl O-3,6-dideoxy-alpha-L-erythro-hexopyranos-4-ulosyl-(1->4)-O-2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1->4)-2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranoside, 2'',3'-anhydride
- (7R,8R,10S)-10-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2S,4aS,5aS,7S,9S,9aR,10aR)-2,9-dimethyl-3-oxooctahydro-2H,5aH-dipyrano[2,3-b:4',3'-e][1,4]dioxin-7-yl]oxy}-6-methyltetrahydro-2H-pyran-2-yl]oxy}-7-{[(2S,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-8-ethyl-1,6,8,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione (non-preferred name)
- Rodorubicina
- Rodorubicinum [Latin]
- Rodorubicine [French]
- Rodorubicin
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Found 1 products.
Rodorubicin
CAS:Rodorubicin is a novel tetraglycosidic anthracycline with antitumor activity.Formula:C48H64N2O17Purity:98%Color and Shape:SolidMolecular weight:941.037
