CAS 965-52-6

Nifuroxazide

Description:

Nifuroxazide is an antimicrobial agent primarily used in the treatment of gastrointestinal infections, particularly those caused by bacteria and protozoa. It belongs to the nitrofuran class of compounds and is characterized by its broad-spectrum antibacterial activity. Nifuroxazide works by inhibiting the growth of pathogens, thereby alleviating symptoms associated with diarrhea and other intestinal disorders. The compound is typically administered orally and is known for its low systemic absorption, which minimizes potential side effects. Its chemical structure features a nitrofuran ring, which is crucial for its antimicrobial properties. Nifuroxazide is often favored in clinical settings due to its effectiveness against a variety of pathogens while maintaining a favorable safety profile. Additionally, it is important to note that while it is effective against bacterial infections, it is not suitable for treating viral infections. As with any medication, it is essential to use nifuroxazide under the guidance of a healthcare professional to ensure appropriate use and to mitigate any potential adverse effects.

Formula: C₁₂H₉N₃O₅

InChI: InChI=1/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+

InChI key: InChIKey=YCWSUKQGVSGXJO-UHFFFAOYSA-N

SMILES: C(=NNC(=O)C1=CC=C(O)C=C1)C=2OC(N(=O)=O)=CC2

Synonyms:

• (5-Nitro-2-furfurylidene)(4-hydroxybenzoyl)hydrazine
• 1-(p-Hydroxybenzoyl)-2-(5-nitrofurfurylidene)hydrazine
• 27-109Rc
• 4-Hydroxy-2-(5-Nitrofurfurylidene)Benzohydrazide
• 4-hydroxy-N'-[(1E)-(5-nitrofuran-2-yl)methylidene]benzohydrazide
• 4-hydroxy-N'-[(5-nitrofuran-2-yl)methylidene]benzohydrazide
• 5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone
• 5-Nitro-2-furfurylidene-4-hydroxybenzhydrazide
• Adral
• Antinal
• Bacifurane
• Benzoic acid, 4-hydroxy-, 2-[(5-nitro-2-furanyl)methylene]hydrazide
• Benzoic acid, 4-hydroxy-, [(5-nitro-2-furanyl)methylene]hydrazide
• Benzoic acid, p-hydroxy-, (5-nitrofurfurylidene)hydrazide
• Diarlidan
• Dicoferin
• Enterofuril
• Ercefurol
• Ercefuryl
• Nifurocazide
• Nifuroxazid
• Pentofuryl
• Rc 27109
• Rc 30-109
• p-Hydroxybenzoic acid (5-nitrofurfurylidene) hydrazide
• Nifuroxazide
• 4-hydroxy-benzoicaci((5-nitro-2-furanyl)methylene)hydrazide
• r.c.27-109
• 4-Hydroxybenzoic acid-[[5-nitro-2-furanyl] methylene] hydrazide
• 4-Hydroxybenzoic Acid 2-[(5-Nitro-2-furanyl)methylene]hydrazide
• NIFUROXAZIDE VETRANAL, 250 MG
• nitrofuroxazide
• (nitro-5’furfurylidene-2’)hydroxy-4benzhydrazide

Nifuroxazide

CAS: 965-52-6

Color and Shape: Yellow

Ref: 61-FOR0574.00

NIFUROXAZIDE CRS

CAS: 965-52-6

NIFUROXAZIDE CRS

Formula: C₁₂H₉N₃O₅

Molecular weight: 275.217

Ref: 41-Y0000836

Nifuroxazide

CAS: 965-52-6

Formula: C₁₂H₉N₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 275.2170

Ref: IN-DA003T3T

Nifuroxazide

CAS: 965-52-6

Nifuroxazide (Diarlidan), an oral nitrofuran antidiarrheal, blocks STAT1/3/5 activation.

Formula: C₁₂H₉N₃O₅

Purity: 99.79% - 99.95%

Color and Shape: Yellow Solid

Molecular weight: 275.22

Ref: TM-T1563

Nifuroxazide

CAS: 965-52-6

Nifuroxazide

Purity: ≥98%

Molecular weight: 275.22g/mol

Ref: 54-BUP16811

Nifuroxazide-d4

CAS: 1188487-83-3, 965-52-6

Formula: C₁₂H₅D₄N₃O₅

Color and Shape: Yellow Solid

Molecular weight: 279.24

Ref: 4Z-N-141

Nifuroxazide

CAS: 965-52-6

Nifuroxazide

Purity: 99%

Molecular weight: 275.22g/mol

Ref: 54-OR1030014

Nifuroxazide

CAS: 965-52-6

Formula: C₁₂H₉N₃O₅

Color and Shape: Neat

Molecular weight: 275.22

Ref: 04-C15523000

Nifuroxazide

CAS: 965-52-6

Formula: C₁₂H₉N₃O₅

Purity: >98.0%(T)

Color and Shape: White to Yellow to Green powder to crystal

Molecular weight: 275.22

Ref: 3B-N1181

Nifuroxazide

CAS: 965-52-6

Color and Shape: Neat

Ref: 86-MM0574.00

Nifuroxazide

Controlled Product

CAS: 965-52-6

Applications Nifuroxazide is an intestinal antiseptic. Nifuroxazide, is still used as a veterinary drug illegally in some countries. SEE H829102 as a test for antibiotic in broiler chickens.
References Carron, M.C.E., et al.: Ann. Pharm. Fr., 21, 287 (1963), Thabaut, A., et al.: Gaz. Med. Fr., 85, 4516 (1978), Residue depletion of nifuroxazide in broiler chicken. Gao F. et al, J Sci Food Agric. 2013 Jul;93(9):2172-8

Formula: C₁₂H₉N₃O₅

Color and Shape: Yellow

Molecular weight: 275.22

Ref: TR-N458500

Nifuroxazide

CAS: 965-52-6

Nifuroxazide is a nitrofuran antibacterial agent that inhibits the synthesis of macromolecules, such as DNA, RNA, and proteins. It is used to treat infectious diseases such as tuberculosis, leprosy, and malaria. Nifuroxazide has also been shown to induce apoptosis in human osteosarcoma cells by inhibiting signal pathways involved in energy metabolism. In addition, nifuroxazide has been shown to inhibit the growth of tumor cell lines in vitro. This drug can be used for the treatment of cancer because it induces pro-apoptotic protein expression and has anticancer activity against a variety of tumor cell lines.

Formula: C₁₂H₉N₃O₅

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 275.22 g/mol

Ref: 3D-FN26215

Nifuroxazide

CAS: 965-52-6

Purity: 98%

Molecular weight: 275.2200012

Ref: 10-F847795