CAS 96719-63-0

6-Isoquinolinol, 1-(4-fluorophenyl)-1,2,3,4-tetrahydro-2-phenyl-

Description:

6-Isoquinolinol, 1-(4-fluorophenyl)-1,2,3,4-tetrahydro-2-phenyl- is a chemical compound characterized by its complex structure, which includes an isoquinoline moiety and a tetrahydro-2-phenyl group. This compound features a fluorinated phenyl group, which can influence its electronic properties and reactivity. Typically, isoquinolinols exhibit properties such as being weakly basic due to the presence of the hydroxyl group, which can participate in hydrogen bonding. The tetrahydro structure contributes to its stereochemistry, potentially affecting its biological activity. Compounds of this nature are often studied for their pharmacological properties, as they may interact with various biological targets. The presence of the fluorine atom can enhance lipophilicity and metabolic stability, making such compounds of interest in medicinal chemistry. As with many organic compounds, the solubility, melting point, and other physical properties would depend on the specific conditions and the presence of functional groups. Overall, this compound represents a class of molecules that may have significant implications in drug development and chemical research.

Formula: C₂₁H₁₈FNO

Synonyms:

• 1-(4-Fluorophenyl)-1,2,3,4-tetrahydro-2-phenyl-6-isoquinolinol

Estrogen receptor modulator 11

CAS: 96719-63-0

Estrogen receptor modulator11 (Compound 27) is a tetrahydroisoquinoline derivative. It exhibits affinity for the estrogen receptor (ER), with IC50 values of 285 nM for ERα and 421 nM for ERβ. Estrogen receptor modulator11 does not demonstrate antagonist activity in MCF-7 cell assays.

Formula: C₂₁H₁₈FNO

Color and Shape: Solid

Molecular weight: 319.372

Ref: TM-T205569