CAS 97135-07-4

2,5-Hexanedione-1,1,1,3,3,4,4,6,6,6-d10(9CI)

Description:

2,5-Hexanedione-1,1,1,3,3,4,4,6,6,6-d10, also known by its CAS number 97135-07-4, is a deuterated form of 2,5-hexanedione, a diketone compound. This substance features a six-carbon chain with two carbonyl (C=O) groups located at the second and fifth positions. The presence of deuterium (d10) indicates that ten hydrogen atoms in the molecule have been replaced with deuterium isotopes, which can be useful in various analytical applications, including NMR spectroscopy. The compound is typically a colorless liquid with a characteristic odor and is soluble in organic solvents. It is primarily used in research and industrial applications, particularly in the synthesis of other organic compounds and as a tracer in metabolic studies. Due to its diketone structure, it may exhibit reactivity typical of carbonyl compounds, such as undergoing nucleophilic addition reactions. Safety precautions should be taken when handling this substance, as diketones can be irritants and may pose health risks upon exposure.

Formula: C₆D₁₀O₂

Synonyms:

• 2,5-Hexanedione-D10
• 2,5-Hexanedione-D

2,5-Hexanedione-d10

CAS: 97135-07-4

Formula: CD₃COCD₂CD₂COCD₃

Purity: 98 atom % D

Color and Shape: Colorless-Pale Yellow Liquid

Molecular weight: 124.13085

Ref: 3U-D2296

2,5-Hexanedione-d10

Controlled Product

CAS: 97135-07-4

Applications 2,5-Hexanedione-d10 is the deuterium labelled form of 2,5-Hexanedione (H292490), which is the metabolite implicated in n-hexane neurotoxicity.
References Abou-Donia, M., et al.: Biochem. Pharmacol., 27, 2055 (1978); Abou-Donia, M., et al.: Biochem. Pharmacol., 27, 2055 (1978); DeCaprio, A., et al.: Brain Res., 586, 219 (1992); LoPachin, R., et al.: Toxicol. Sci., 86, 214 (2005);

Formula: C₆D₁₀O₂

Color and Shape: Neat

Molecular weight: 124.2

Ref: TR-H292492

2,5-Hexanedione-d10

CAS: 97135-07-4

2,5-Hexanedione-d10 is a medicinal compound that has been shown to have potent anticancer properties. It is an analog of 2,5-hexanedione and contains deuterium atoms at specific positions in its molecular structure. This compound has been studied extensively for its ability to induce apoptosis in cancer cells and inhibit tumor growth. In Chinese hamster ovary cells, 2,5-Hexanedione-d10 has been shown to inhibit protein kinase activity and cell cycle progression. This compound also acts as an inhibitor of certain kinases that are involved in the regulation of cellular processes such as proliferation and differentiation. Additionally, 2,5-Hexanedione-d10 has been detected in human urine samples and may have potential as a biomarker for cancer diagnosis or treatment monitoring.

Formula: C₆H₁₀O₂

Purity: Min. 95%

Molecular weight: 124.2 g/mol

Ref: 3D-XDA13507