CAS 97229-11-3

4-Chloro-2-(methylsulfonyl)pyrimidine

Description:

4-Chloro-2-(methylsulfonyl)pyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with a chlorine atom and a methylsulfonyl group. Its molecular formula is C6H6ClN3O2S, indicating the presence of carbon, hydrogen, chlorine, nitrogen, oxygen, and sulfur atoms. This compound typically appears as a solid and is soluble in polar organic solvents. It exhibits properties such as moderate stability under standard conditions, but may be sensitive to strong bases or acids. The presence of the methylsulfonyl group contributes to its potential as a versatile building block in medicinal chemistry, particularly in the development of pharmaceuticals. Additionally, the chlorine atom can influence the compound's reactivity and biological activity, making it of interest in various chemical syntheses and applications. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance. Overall, 4-Chloro-2-(methylsulfonyl)pyrimidine is notable for its structural features and potential utility in chemical research and development.

Formula: C₅H₅ClN₂O₂S

InChI: InChI=1/C5H5ClN2O2S/c1-11(9,10)5-7-3-2-4(6)8-5/h2-3H,1H3

InChI key: InChIKey=BWVZLXTZQHILRC-UHFFFAOYSA-N

SMILES: S(C)(=O)(=O)C=1N=C(Cl)C=CN1

Synonyms:

• Pyrimidine, 4-chloro-2-(methylsulfonyl)-
• 4-Chloro-2-(methylsulfonyl)pyrimidine
• CMSP
• 4-Chloro-2-(methylsulfonyl)
• 4-CHLORO-2-METHANESULFONYL-PYRIMIDINE
• 4-Chloro-2-(methylsulfonyl)pyrimidine ,98%

Pyrimidine, 4-chloro-2-(methylsulfonyl)-

CAS: 97229-11-3

Formula: C₅H₅ClN₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 192.6234

Ref: IN-DA00IJX3

4-Chloro-2-(methylsulfonyl)pyrimidine

CAS: 97229-11-3

4-Chloro-2-(methylsulfonyl)pyrimidine

Purity: 98%

Color and Shape: Solid

Molecular weight: 192.62g/mol

Ref: 54-OR939797

4-Chloro-2-(methylsulfonyl)pyrimidine

CAS: 97229-11-3

Formula: C₅H₅ClN₂O₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 192.62

Ref: 10-F228074

4-Chloro-2-(methylsulfonyl)pyrimidine

CAS: 97229-11-3

4-Chloro-2-(methylsulfonyl)pyrimidine is a modification of the drug tak-659 with high oral bioavailability. It has been evaluated for its x-ray crystallographic properties, and found to have similar binding affinity to tyrosine kinases as tak-659. 4-Chloro-2-(methylsulfonyl)pyrimidine has also been shown to have permeability in human erythrocytes and an oral bioavailability of 2%. It is a potential candidate for the treatment of various types of cancer, including those that are resistant to currently available drugs, such as chronic myeloid leukemia or acute lymphoblastic leukemia.

Formula: C₅H₅ClN₂O₂S

Purity: Min. 95%

Molecular weight: 192.62 g/mol

Ref: 3D-FC142333