CAS 97519-39-6

Ceftibuten

Description:

Ceftibuten is a third-generation cephalosporin antibiotic, primarily used to treat bacterial infections. It exhibits a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, making it effective for respiratory tract infections, urinary tract infections, and certain skin infections. The chemical structure of ceftibuten includes a beta-lactam ring, which is essential for its antibacterial activity, as it interferes with bacterial cell wall synthesis. Ceftibuten is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and a relatively long half-life, allowing for once-daily dosing. It is generally well-tolerated, although potential side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, hematological effects. As with other antibiotics, the emergence of resistance is a concern, necessitating appropriate use to preserve its efficacy. Ceftibuten is classified under the ATC code J01DD15 and is often prescribed when other antibiotics may not be suitable due to resistance or patient-specific factors.

Formula: C₁₅H₁₄N₄O₆S₂

InChI: InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1

InChI key: InChIKey=UNJFKXSSGBWRBZ-BJCIPQKHSA-N

SMILES: O=C1N2[C@@]([C@@H]1NC(/C(=C\CC(O)=O)/C3=CSC(N)=N3)=O)(SCC=C2C(O)=O)[H]

Synonyms:

• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]amino]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-(2-amino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-
• 7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 7432S
• Antibiotic 7432S
• Cedax
• Ceftibuten (SCH 39720)
• Cephalosporin 7432-S
• S 7432
• Sch 39720

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CAS: 97519-39-6

Formula: C₁₅H₁₄N₄O₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.4249

Ref: IN-DA019FUL

Ceftibuten

CAS: 97519-39-6

Formula: C₁₅H₁₄N₄O₆S₂

Color and Shape: Pale Yellow Solid

Molecular weight: 410.42

Ref: 4Z-C-1091

Ceftibuten Hydrate

CAS: 118081-34-8, 118081-35-9, 118081-37-1, 97519-39-6

Formula: C₁₅H₁₄N₄O₆S₂·xH₂O

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 410.42 (as Anhydrous)

Ref: 3B-C3391

Ceftibuten hydrate

CAS: 97519-39-6

Formula: C₁₅H₁₄N₄O₆S₂·xH₂O

Purity: ≤ 1.0%

Color and Shape: White to pale yellow crystalline powder

Molecular weight: 410.42 (anhydrous)

Ref: 7W-GA7818

Ceftibuten-13C3

Controlled Product

CAS: 97519-39-6

Applications A labelled third-generation cephalosporin antibiotic used in the treatment of respiratory tract infection, urinary tract infection, enteritis and gastroenteritis
References Guest, N. et al.: Int. J. Antimicrob. Agents, 10, 49 (1998); Hamashima, Y., et al.: J. Antibiot., 40, 1468 (1987); Nakashima, M., et al.: J. Clin. Pharmacol., 28, 246 (1988);

Formula: C₃C₁₂H₁₄N₄O₆S₂

Color and Shape: Neat

Molecular weight: 413.403

Ref: TR-C244507

Ceftibuten

CAS: 97519-39-6

Ceftibuten is a third-generation cephalosporin antibiotic.

Formula: C₁₅H₁₄N₄O₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.42

Ref: TM-T10753

Ceftibuten

CAS: 97519-39-6

Ceftibuten is a third-generation cephalosporin antibiotic, which is a beta-lactam class of antimicrobial agents derived from Acremonium, a genus of fungi. This product is synthesized to resist degradation by beta-lactamase enzymes, which are commonly produced by resistant bacteria, thereby maintaining its efficacy against a wide range of bacterial pathogens.

Formula: C₁₅H₁₄N₄O₆S₂

Purity: Min. 95%

Molecular weight: 410.43 g/mol

Ref: 3D-FC176429