CAS 97627-27-5

Urea,N-4-pyridinyl-N'-(2,4,6-trichlorophenyl)-

Description:

Urea, N-4-pyridinyl-N'-(2,4,6-trichlorophenyl)-, identified by CAS number 97627-27-5, is a chemical compound that features a urea functional group substituted with a pyridine ring and a trichlorophenyl moiety. This compound typically exhibits characteristics associated with both urea derivatives and aromatic compounds, such as moderate solubility in polar solvents and potential biological activity due to its heterocyclic structure. The presence of the pyridine ring may impart basic properties, while the trichlorophenyl group can enhance lipophilicity and influence the compound's reactivity. Urea derivatives are often studied for their applications in pharmaceuticals, agrochemicals, and as intermediates in organic synthesis. The specific arrangement of substituents in this compound may also affect its interaction with biological targets, making it of interest in medicinal chemistry. As with many chemical substances, safety and handling precautions should be observed, given the potential toxicity associated with chlorinated aromatic compounds.

Formula: C₁₂H₈Cl₃N₃O

Synonyms:

• N-(4-Pyridyl)-N’-(2,4,6-Trichlorophenyl)Urea
• Rho-Kinase Inhibitor Ii
• N-4-Pyridinyl-N’-(2,4,6-trichlorophenyl)urea

N-(4-Pyridyl)-N’-(2,4,6-trichlorophenyl)urea

Controlled Product

CAS: 97627-27-5

Stability Light Sensitive
Applications A pyridyl urea compound that acts as a potent, selective, and ATP-competitive inhibitor of Rho-associated protein kinase(ROCK).
References Hansch, C., et al.: J. Pharm. Sci., 62, 1 (1973), Pavia, M., et al.: J. Med. Chem., 33, 854 (1990), Sridhar, S., et al.: Eur. J. Pharm. Sci., 16, 129 (2002), Takami, A., et al.: Bioorg. Med. Chem., 12, 2115 (2004),

Formula: C₁₂H₈Cl₃N₃O

Color and Shape: Neat

Molecular weight: 316.57

Ref: TR-P997000