CAS 97747-88-1

Lilopristone

Description:

Lilopristone, with the CAS number 97747-88-1, is a synthetic steroid compound that functions primarily as a selective progesterone receptor modulator (SPRM). It is characterized by its ability to bind to progesterone receptors, influencing various biological processes related to reproductive health. Lilopristone exhibits anti-progestational effects, making it of interest in the fields of contraception and reproductive medicine. The compound is known for its potential to inhibit the effects of progesterone, which is crucial for maintaining pregnancy. Additionally, it has been studied for its applications in managing conditions such as endometriosis and uterine fibroids. Lilopristone's pharmacological profile includes a favorable safety margin, although its use is subject to regulatory scrutiny and clinical evaluation. As with many synthetic hormones, the specific effects and side effects can vary based on dosage and individual response. Overall, lilopristone represents a significant area of research in hormonal therapies and reproductive health.

Formula: C₂₉H₃₇NO₃

InChI: InChI=1S/C29H37NO3/c1-28-18-25(19-5-8-21(9-6-19)30(2)3)27-23-12-10-22(32)17-20(23)7-11-24(27)26(28)13-15-29(28,33)14-4-16-31/h4-6,8-9,14,17,24-26,31,33H,7,10-13,15-16,18H2,1-3H3/b14-4-/t24-,25+,26-,28-,29-/m0/s1

InChI key: InChIKey=RCOWGILQXUPXEW-FUSOFXSQSA-N

SMILES: C[C@@]12[C@]([C@]3(C([C@](C1)(C4=CC=C(N(C)C)C=C4)[H])=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(/C=C\CO)O)[H]

Synonyms:

• (11beta,17beta)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-3-hydroxyprop-1-en-1-yl]estra-4,9-dien-3-one
• (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-3-hydroxy-1-propen-1-yl]estra-4,9-dien-3-one
• Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-3-hydroxy-1-propen-1-yl]-, (11β,17β)-
• Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-3-hydroxy-1-propenyl]-, (11β,17β)-
• Zk 98734

Lilopristone

CAS: 97747-88-1

Formula: C₂₉H₃₇NO₃

Purity: 98%

Molecular weight: 447.6090

Ref: IN-DA00IJZ7

Lilopristone

Controlled Product

CAS: 97747-88-1

Applications Lilopristone is a progesterone antagonist.
References Puri, C., et al.: Am. J. Obstet. Gynecol., 161, 248 (1989)

Formula: C₂₉H₃₇NO₃

Color and Shape: Neat

Molecular weight: 447.609

Ref: TR-L440005

Ligustrazine HCl

Controlled Product

CAS: 97747-88-1

Ligustrazine is a plant extract that has been shown to inhibit platelet aggregation and has anti-inflammatory properties. It also inhibits the production of nitric oxide, which may be related to its antiplatelet activity. Ligustrazine HCl is used as a pharmaceutical drug for the treatment of cardiovascular diseases such as hypertension and angina pectoris. Ligustrazine HCl inhibits the phosphodiesterase activity by blocking the enzyme's active site, thereby increasing levels of cyclic AMP (cAMP). This increase in cAMP leads to a decrease in calcium concentration, which reduces platelet aggregation. In addition, ligustrazine may have effects on glucose metabolism by inhibiting glucose injection into cells after an incubation period. This inhibitory effect also results in reduced insulin release from pancreatic beta cells and decreased glycogenolysis in liver cells. Ligustrazine HCl is also used in Chinese medicine to treat diabetes mellitus type II and

Formula: C₈H₁₂N₂·HCl

Purity: Min. 95%

Molecular weight: 172.66 g/mol

Ref: 3D-FL33460

Lilopristone

CAS: 97747-88-1

Lilopristone is an antagonist of progesterone.

Formula: C₂₉H₃₇NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 447.61

Ref: TM-T20747