CAS 97792-45-5

Lappaconitine hydrobromide

Description:

Lappaconitine hydrobromide is a chemical compound derived from the plant genus Aconitum, commonly known as monkshood. It is classified as an alkaloid, specifically a type of aconitine, which is known for its potent pharmacological effects. This compound typically appears as a white to off-white crystalline powder and is soluble in water and alcohol, making it suitable for various applications in medicinal chemistry. Lappaconitine hydrobromide exhibits analgesic and anti-inflammatory properties, which have been explored for potential therapeutic uses, particularly in pain management. However, it is important to note that compounds from the Aconitum species can be highly toxic, and their use must be approached with caution due to the risk of severe side effects, including cardiovascular and neurological complications. As with many alkaloids, the pharmacokinetics and safety profile of lappaconitine hydrobromide require thorough investigation before clinical application. Proper handling and dosage are critical to mitigate toxicity risks associated with this compound.

Formula: C₃₂H₄₄N₂O₈·BrH

InChI: InChI=1S/C32H44N2O8.BrH/c1-6-34-16-29(42-28(36)18-9-7-8-10-21(18)33-17(2)35)12-11-25(40-4)31-23(29)14-20(26(31)34)30(37)15-22(39-3)19-13-24(31)32(30,38)27(19)41-5;/h7-10,19-20,22-27,37-38H,6,11-16H2,1-5H3,(H,33,35);1H/t19-,20+,22+,23-,24+,25+,26-,27+,29-,30+,31+,32+;/m1./s1

InChI key: InChIKey=CFFYROOPXPKMEQ-IPZKEBFRSA-N

SMILES: O(C)[C@@H]1[C@@]23[C@]4([C@](OC(=O)C5=C(NC(C)=O)C=CC=C5)(CN(CC)[C@@]2([C@](C4)([C@]6(O)[C@]7(O)[C@]3(C[C@@]([C@@H]7OC)([C@@H](OC)C6)[H])[H])[H])[H])CC1)[H].Br

Synonyms:

• (1a,14a,16b)-20-Ethyl-1,14,16-trimethoxyaconitane-4,8,9-triol 4-(2-(acetylamino)benzoate) hydrobromide
• 2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-4,8,9-triol deriv.
• Aconitane-4,8,9-triol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], hydrobromide (1:1), (1α,14α,16β)-
• Aconitane-4,8,9-triol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], monohydrobromide, (1α,14α,16β)-
• Allafort
• Allapinine
• Lappaconite Hydrobromide
• Lappaconitin hydrobromide
• Lappaconitine hydrobromide

Lappaconitine Hydrobromide

CAS: 32854-75-4, 97792-45-5

Formula: C₃₂H₄₄N₂O₈·HBr

Purity: >95.0%(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 665.62

Ref: 3B-L0272

Lappaconitine hydrobromide

CAS: 97792-45-5

Formula: C₃₂H₄₅BRN₂O₈

Molecular weight: 665.62

Ref: 7W-GY7380

Lappaconitine hydrobromide

CAS: 97792-45-5

Formula: C₃₂H₄₅BrN₂O₈

Purity: 95%~99%

Molecular weight: 665.622

Ref: BP-BP0843

Lappaconitine hydrobromide

CAS: 97792-45-5

Lappaconitine hydrobromide (Allapinine) is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.

Formula: C₃₂H₄₄N₂O₈·HBr

Purity: 97.23%

Color and Shape: White Powder

Molecular weight: 665.61

Ref: TM-T6560

Lappaconitine Hydrobromide

Controlled Product

CAS: 97792-45-5

Applications Hydrobromide salt of (+)-Lappaconitine (L175850), a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Xu, M. et al.: Lat. Am. J. Pharm., 32, 1433 (2013); Yunusov, M.et al.: Russ. Chem. Bull., 60, 633 (2011);

Formula: C₃₂H₄₅BrN₂O₈

Color and Shape: White To Off-White

Molecular weight: 665.61

Ref: TR-L175855

Lappaconitine Hydrobromide

Controlled Product

CAS: 97792-45-5

Hydrobromide form of lappaconitine, lappaconitine hydrobromide is clinically used to reduce swelling and inflammation while providing a local anesthetic effect. The molecular structure of lappaconitine was first reported in 1895. Traditionally used for pain relief, lappaconitine is a plant-derived C18-diuterpenoid alkaloid. In rats, the antinociceptive action of lappaconitine has been shown to be based on the enhanced expression of dynorphin A in the spinal microglia.

Formula: C₃₂H₄₄N₂O₈·HBr

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 665.61 g/mol

Ref: 3D-FL59926