CAS 97867-34-0

Norfloxacin lactate

Description:

Norfloxacin lactate is a derivative of norfloxacin, which is a fluoroquinolone antibiotic. It is primarily used for its antibacterial properties, particularly against a range of Gram-negative and some Gram-positive bacteria. The lactate form enhances its solubility and stability, making it suitable for various pharmaceutical formulations. Norfloxacin lactate exhibits characteristics typical of fluoroquinolones, including the ability to inhibit bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication and transcription. This compound is often utilized in the treatment of urinary tract infections and other bacterial infections. In terms of physical properties, norfloxacin lactate is typically a white to off-white crystalline powder, and it is soluble in water, which facilitates its use in injectable formulations. As with other antibiotics, it is important to use norfloxacin lactate judiciously to prevent the development of antibiotic resistance. Safety and efficacy profiles should be considered, and it is essential to follow appropriate dosing guidelines to minimize potential side effects.

Formula: C₁₆H₁₈FN₃O₃·C₃H₆O₃

InChI: InChI=1S/C16H18FN3O3.C3H6O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20;1-2(4)3(5)6/h7-9,18H,2-6H2,1H3,(H,22,23);2,4H,1H3,(H,5,6)

InChI key: InChIKey=AYEXIHJJZPTXSS-UHFFFAOYSA-N

SMILES: C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCNCC3.C(C(O)=O)(C)O

Synonyms:

• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, mono(2-hydroxypropanoate)
• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, compd. with 2-hydroxypropanoic acid (1:1)
• Propanoic acid, 2-hydroxy-, compd. with 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (1:1)
• Norfloxacin lactate

Norfloxacin lactate

CAS: 97867-34-0

Norfloxacin lactate is a synthetic antibacterial agent, derived from fluoroquinolone antibiotics, which acts by inhibiting bacterial DNA gyrase, an essential enzyme for DNA replication. This mode of action disrupts the supercoiling process required for bacterial DNA synthesis, leading to a bactericidal effect.

Formula: C₁₉H₂₄FN₃O₆

Purity: Min. 95%

Molecular weight: 409.4 g/mol

Ref: 3D-XDA86734