CAS 979-32-8

Estradiol valerate

Description:

Estradiol valerate is a synthetic form of the naturally occurring estrogen estradiol, commonly used in hormone replacement therapy and contraceptive formulations. It is characterized by its esterified form, which enhances its lipid solubility and prolongs its action in the body. The chemical structure consists of a phenolic A-ring, a cyclopentane D-ring, and a valerate ester side chain, which contributes to its pharmacokinetic properties. Estradiol valerate is typically administered via intramuscular injection or oral routes, and it is known for its effectiveness in alleviating menopausal symptoms, regulating menstrual cycles, and supporting reproductive health. The substance is generally well-tolerated, but potential side effects may include nausea, headaches, and changes in mood. As with other estrogens, it is important to monitor for risks associated with long-term use, such as thromboembolic events. Estradiol valerate is classified under the category of steroid hormones and is recognized for its role in various physiological processes, including the regulation of the menstrual cycle and maintenance of secondary sexual characteristics.

Formula: C₂₃H₃₂O₃

InChI: InChI=1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t18-,19-,20+,21+,23+/m1/s1

InChI key: InChIKey=RSEPBGGWRJCQGY-RBRWEJTLSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2OC(CCCC)=O)[H]

Synonyms:

• (17Beta)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl Pentanoate
• (8Xi,9Xi,14Xi,17Beta)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl Pentanoate
• 1,3,5(10)-Estratriene-3,17B-Diol 17-Pentanote
• 3-Hydroxy-17β-valeroyloxyestra-1,3,5(10)-triene
• 3-Hydroxyestra-1,3,5(10)-Trien-17-Yl Pentanoate
• Atladiol
• Climaval
• Deladiol
• Delahormone unimatic
• Delestrogen
• Delestrogen 4x
• Dura-Estradiol
• Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-pentanoate
• Estra-1,3,5(10)-triene-3,17β-diol 17-valerate
• Estradiol 17β-valerate
• Estradiol Valeate
• Estradiol valerate
• Estradiol valerianate
• Estradiol-17-Valerate
• Estradiolvalerat
• Estraval
• Femogex
• Gynogen LA
• Gynogen LA 40
• Gynokadin
• Meriestra
• Neofollin
• Nsc 17590
• Nuvelle
• Oestradiol Valerate
• Oestradiol valerinate
• Pelanin Depot
• Pharlon
• Primofol-Depot
• Primogyn-Depot
• Progynon-Depot
• Progynova
• Valerate D'Estradiol
• Valerato De Estradiol
• Valergen

β-Estradiol 17-Valerate

CAS: 979-32-8

Formula: C₂₃H₃₂O₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 356.51

Ref: 3B-E0876

Estradiol valeate

CAS: 979-32-8

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 371.521

Ref: 10-F463586

ESTRADIOL VALERATE FOR SYSTEM SUITABILITY CRS

CAS: 979-32-8

ESTRADIOL VALERATE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001823

ESTRADIOL VALERATE CRS

CAS: 979-32-8

ESTRADIOL VALERATE CRS

Formula: C₂₃H₃₂O₃

Color and Shape: Added Modified

Molecular weight: 356.4984

Ref: 41-Y0000046

ESTRADIOL VALERATE RS

CAS: 979-32-8

ESTRADIOL VALERATE RS

Ref: 41-ICRS66491

Estradiol Valerate

CAS: 979-32-8

Estrogens and progestins

Formula: C₂₃H₃₂O₃

Color and Shape: White Crystalline Powder

Molecular weight: 356.23514

Ref: 45-1254009

3-Hydroxy-17β-valeroyloxyestra-1,3,5(10)-trien

CAS: 979-32-8

Formula: C₂₃H₃₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 356.4984

Ref: IN-DA0036S0

Estradiol Valerate

CAS: 979-32-8

Formula: C₂₃H₃₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 356.51

Ref: 4Z-E-0927

β-Estradiol 17-Valerate

CAS: 979-32-8

β-Estradiol 17-Valerate

Purity: 98%

Molecular weight: 356.5g/mol

Ref: 54-OR1029038

Estradiol valerate

CAS: 979-32-8

Formula: C₂₃H₃₂O₃

Molecular weight: 356.50

Ref: 7W-GK7108

Estradiol valerate

CAS: 979-32-8

β-estradiol 17-valerate (EV) is a synthetic estrogen. In hormone replacement therapy drugs, it is widely used in combination with other steroid hormones.

Formula: C₂₃H₃₂O₃

Purity: 99.11% - 99.9%

Color and Shape: Na

Molecular weight: 356.51

Ref: TM-T0135

Estradiol Valerate

Controlled Product

CAS: 979-32-8

Formula: C₂₃H₃₂O₃

Color and Shape: Neat

Molecular weight: 356.50

Ref: 86-MM0209.00

Estradiol 17-Valerate

Controlled Product

CAS: 979-32-8

Applications Estradiol (E888000) derivative. An estrogen.
References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),

Formula: C₂₃H₃₂O₃

Color and Shape: White To Off-White

Molecular weight: 356.50

Ref: TR-E888860

Estradiol 17-valerate

CAS: 979-32-8

Estradiol is a form of the hormone estrogen that has been modified to be more lipophilic. It is used in combination with other drugs to treat menopausal symptoms and as an adjuvant for the treatment of breast cancer in women. Estradiol 17-valerate is also used in the treatment of schizophrenia, although not as often as estradiol valerate, because it has a shorter duration of action. The mechanism of action is thought to be due to its ability to increase the concentration of dopamine at nerve terminals by blocking reuptake or inhibiting its metabolism. This may result in relief from distal tubule dysfunction and an improvement in urinary tract symptoms associated with benign prostatic hypertrophy. There are many other possible mechanisms of action including the prevention of bone loss, increased bone age, and increased NMDA receptor binding potentials.

Formula: C₂₃H₃₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 356.5 g/mol

Ref: 3D-FE22827

Estradiol Valerate

CAS: 979-32-8

Formula: C₂₃H₃₂O₃

Molecular weight: 356.4

Ref: ST-EA-CP-E61000

Estradiol Valerate

CAS: 979-32-8

Color and Shape: Neat

Ref: 61-FOR0209.00