CAS 97919-22-7

4-Amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide

Description:

4-Amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide, with the CAS number 97919-22-7, is a chemical compound that belongs to the class of sulfonamides, which are characterized by the presence of a sulfonamide functional group (-SO2NH2). This compound features an amino group (-NH2) and a chloro-substituted quinoxaline moiety, contributing to its potential biological activity. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents. The presence of the quinoxaline structure suggests potential applications in medicinal chemistry, particularly in the development of antimicrobial or anticancer agents, as quinoxalines are known for their diverse biological properties. The sulfonamide group may also enhance the compound's pharmacological profile by improving its interaction with biological targets. Safety and handling precautions should be observed, as with many chemical substances, due to potential toxicity or reactivity. Overall, this compound represents a specific example of a sulfonamide derivative with potential applications in pharmaceutical research.

Formula: C₁₄H₁₁ClN₄O₂S

InChI: InChI=1S/C14H11ClN4O2S/c15-11-2-1-3-12-14(11)17-8-13(18-12)19-22(20,21)10-6-4-9(16)5-7-10/h1-8H,16H2,(H,18,19)

InChI key: InChIKey=CTSNHMQGVWXIEG-UHFFFAOYSA-N

SMILES: ClC=1C2=C(N=C(NS(=O)(=O)C3=CC=C(N)C=C3)C=N2)C=CC1

Synonyms:

• 4-Amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide
• Chlorsulfaquinoxaline
• NSC 339004
• benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)-
• CQS

Chloroquinoxaline sulfonamide

CAS: 97919-22-7

Chloroquinoxaline sulfonamide

Purity: ≥98%

Molecular weight: 334.78g/mol

Ref: 54-BUP12527

Chlorsulfaquinoxaline

CAS: 97919-22-7

Applications Chlorsulfaquinoxaline is used to prepare carbonic anhydrase inhibitors 1,3,4-thiadiazole-2-sulfonamide derivatives as antitumor agents.
References Supuran, C., et al.: Eur. J. Med. Chem., 35, 867 (2000)

Formula: C₁₄H₁₁ClN₄O₂S

Color and Shape: Neat

Molecular weight: 334.78

Ref: TR-C426000

Chlorsulfaquinoxaline

CAS: 97919-22-7

Chlorsulfaquinoxaline is a chiral sulfonamide that inhibits the activity of cyclooxygenase-2 (COX-2) and 5-lipoxygenase. It has been shown to inhibit tumor growth in animal models of metastatic colorectal cancer as well as bowel disease. In addition, Chlorsulfaquinoxaline has been shown to have clinical relevance for inflammatory bowel disease and primary sclerosing cholangitis.
Chlorsulfaquinoxaline is an inhibitor of the COX-2 and 5-lipoxygenase enzymes, which are key enzymes in prostaglandin synthesis. It has been shown to inhibit tumor growth in animal models of metastatic colorectal cancer as well as bowel disease. In addition, Chlorsulfaquinoxaline has been shown to have clinical relevance for inflammatory bowel disease and primary sclerosing cholangitis.

Formula: C₁₄H₁₁ClN₄O₂S

Purity: Min. 95%

Molecular weight: 334.8 g/mol

Ref: 3D-XDA91922

Chloroquinoxaline sulfonamide

CAS: 97919-22-7

Chloroquinoxaline sulfonamide (Chloroquinoxaline) is an organic micropollutant with antimicrobial activity.

Formula: C₁₄H₁₁ClN₄O₂S

Purity: 99.79% - 99.89%

Color and Shape: Solid

Molecular weight: 334.78

Ref: TM-T14953