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CAS 97974-93-1

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Uridine,2'-deoxy-5-(2-hydroxyethyl)-, 3',5'-bis(4-methylbenzoate) (9CI)

Description:
Uridine, 2'-deoxy-5-(2-hydroxyethyl)-, 3',5'-bis(4-methylbenzoate) is a synthetic derivative of uridine, a nucleoside that plays a crucial role in cellular metabolism and RNA synthesis. This compound features a modified sugar moiety, specifically a 2'-deoxy configuration, which is characteristic of DNA nucleosides. The presence of two 4-methylbenzoate ester groups enhances its lipophilicity, potentially improving membrane permeability and bioavailability. The hydroxyethyl substituent contributes to its solubility and may influence its interaction with biological targets. As a chemical entity, it may exhibit properties such as stability under physiological conditions, and its structure suggests potential applications in medicinal chemistry, particularly in the development of nucleoside analogs for therapeutic purposes. The CAS number 97974-93-1 uniquely identifies this compound in chemical databases, facilitating its study and application in research and industry. Overall, this compound represents an interesting modification of a naturally occurring nucleoside, with implications for drug design and biochemistry.
Formula:C27H28N2O8
Synonyms:
  • 3’,5’-Di-O-(P-Toluoyl)-5-(2-Hydroxyethyl)-2’-Deoxyuridine
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Found 1 products.
  • 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine
    Biosynth
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    3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine

    CAS:
    <p>3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.</p>
    Formula:C27H28N2O8
    Purity:Min. 95%
    Molecular weight:508.50 g/mol

    Ref: 3D-XDA97493

    250mg
    1,011.00€