CAS 98-59-9

Tosyl chloride

Description:

Tosyl chloride, also known as p-toluenesulfonyl chloride, is an organic compound with the chemical formula C7H7ClO2S. It is a colorless to pale yellow liquid that is highly reactive and serves as an important reagent in organic synthesis. Tosyl chloride is characterized by its sulfonyl chloride functional group, which makes it a potent electrophile, allowing it to react with nucleophiles to form tosylates. This property is particularly useful in the conversion of alcohols into better leaving groups, facilitating various substitution reactions. The compound has a strong, pungent odor and is soluble in organic solvents such as dichloromethane and ether, but is not soluble in water. Due to its reactivity, tosyl chloride must be handled with care, as it can cause severe irritation to the skin, eyes, and respiratory system. It is commonly used in the preparation of tosylate esters, which are valuable intermediates in the synthesis of pharmaceuticals and other organic compounds. Proper safety precautions, including the use of personal protective equipment, are essential when working with this chemical.

Formula: C₇H₇ClO₂S

InChI: InChI=1S/C7H7ClO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3

InChI key: InChIKey=YYROPELSRYBVMQ-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C1=CC=C(C)C=C1

Synonyms:

• 4-Methylbenzene-1-sulfonyl chloride
• 4-Methylbenzenesulfonyl chloride
• 4-Methylbenzenesulphonyl chloride
• 4-Methylphenylsulfonyl chloride
• 4-Toluene Sulfonyl Chloride
• 4-Toluene sulfochloride
• 4-Toluenesulfonyl chloride
• 4-Toluensulfonyl chloride
• 4-Toluolsulfonyl chloride
• 4-Tosyl chloride
• Benzenesulfonyl chloride, 4-methyl-
• Chlorure de tosyle
• Cloruro De Tosilo
• Nsc 175822
• P-Toluolsulfonylchlorid
• P-toluene Sulphonyl chloride
• P-toluene sulfonyl chloride
• Ptsc
• Toluene-4-sulfonyl chloride
• Toluenesulfonyl chloride
• Tosylchlorid
• p-Methylbenzenesulfonyl chloride
• p-Methylphenylsulfonyl chloride
• p-Toluene Benzyl Sulfonyl Chloride
• p-Toluenesulfochloride
• p-Toluenesulfonic acid chloride
• p-Toluenesulfonic chloride
• p-Toluenesulfonyl chloride
• p-Toluenesulphonyl chloride
• p-Tolylsulfonyl chloride
• p-Tosyl Chloride

p-Toluenesulfonyl Chloride

CAS: 98-59-9

Formula: C₇H₇ClO₂S

Purity: >99.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 190.64

Ref: 3B-T0272

4-Toluenesulphonyl chloride

CAS: 98-59-9

BR1703 - 4-Toluenesulphonyl chloride

Formula: C₇H₇ClO₂S

Purity: 97%

Color and Shape: Solid, White crystalline powder

Molecular weight: 190.64

Ref: 10-BR1703

p-Toluenesulfonyl chloride, 98%

CAS: 98-59-9

p-Toluenesulfonyl chloride is used as a precursor in the production of dyes and saccharin. It acts as a dehydrating agent in the conversion of urea to carbodiimide and converts alcohols into the corresponding toluenesulfonate esters. It is also employed as a flow-promoting agent for paints, an adhes

Formula: C₇H₇ClO₂S

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 190.64

Ref: 02-A14547

Toluene-4-sulphonyl chloride

CAS: 98-59-9

Toluene-4-sulphonyl chloride

Formula: C₇H₇ClO₂S

Purity: 97%

Color and Shape: white crystalline solid

Molecular weight: 190.64728g/mol

Ref: 54-OR9931

p-Toluenesulfonyl chloride

CAS: 98-59-9

Formula: C₇H₇ClO₂S

Purity: ≥ 98.0%

Color and Shape: White to off-white powder to crystalline powder

Molecular weight: 190.65

Ref: 7W-GK4222

p-Toluenesulfonyl Chloride

CAS: 98-59-9

Formula: C₇H₇ClO₂S

Molecular weight: 190.65

Ref: 4Z-K-0123

p-Toluenesulfonyl Chloride

Controlled Product

CAS: 98-59-9

Formula: C₇H₇ClO₂S

Color and Shape: Neat

Molecular weight: 190.65

Ref: TR-T535905

4-Toluenesulfonyl chloride

CAS: 98-59-9

4-Toluenesulfonyl chloride is a tosylate that reacts with amines and n-oxide groups to form sulfonamides. It is used as an antimicrobial agent and as an irreversible enzyme inhibitor. 4-Toluenesulfonyl chloride inhibits enzymes in the bowel, which may be due to its ability to form a disulfide bond with cysteine residues. This compound has been shown to have anti-cancer properties in vitro, where it inhibited the growth of carcinoma cells by inhibiting DNA synthesis. 4-Toluenesulfonyl chloride also has inhibitory properties against nitrogen atoms, which are found in the active site of many enzymes.

Formula: C₇H₇ClO₂S

Purity: Min. 95%

Color and Shape: White Clear Liquid

Molecular weight: 190.65 g/mol

Ref: 3D-FT02715