CAS 98-75-9

N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]propanamide

Description:

N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]propanamide, with the CAS number 98-75-9, is a chemical compound characterized by its unique structure that includes a thiadiazole ring and a sulfonamide group. This compound typically exhibits properties associated with both sulfonamides and thiadiazoles, such as potential antimicrobial activity and the ability to interact with biological systems. It is often utilized in pharmaceutical research due to its biological activity, particularly in the development of drugs targeting various diseases. The presence of the aminosulfonyl group enhances its solubility in polar solvents, making it suitable for various applications in medicinal chemistry. Additionally, the compound may exhibit moderate stability under standard conditions, although it should be handled with care due to potential reactivity with strong oxidizing agents. Overall, N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]propanamide represents a significant interest in the field of drug discovery and development.

Formula: C₅H₈N₄O₃S₂

InChI: InChI=1/C5H8N4O3S2/c1-2-3(10)7-4-8-9-5(13-4)14(6,11)12/h2H2,1H3,(H2,6,11,12)(H,7,8,10)

InChI key: InChIKey=PCBBBQKRWNGNDW-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C=1SC(NC(CC)=O)=NN1

Synonyms:

• N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]propanamide
• Propazolamide
• Propazolamide
• Propazolamide [INN]
• Propionamide, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-
• Propanamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-
• UNII-5E2PXL9FZF
• N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide
• 5-Propionamido-1,3,4-thiadiazole-2-sulfonamide
• 2-Propionamido-1,3,4-thiadiazole-5-sulfonamide

N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)propionamide

CAS: 98-75-9

N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)propionamide

Purity: 95%

Molecular weight: 236.28g/mol

Ref: 54-OR1047352

N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide

CAS: 98-75-9

N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide (NST) is an analog of the drug binding to the cavity of a protein. NST was shown to be active against Gram-positive and Gram-negative bacteria, as well as fungi. It has been shown that NST is a potent inhibitor of fatty acid biosynthesis in bacteria. The biological properties of NST have also been studied by reconstituting it with fatty alcohols, which are used as excipients in pharmaceutical preparations. Chromatographic methods were used to analyze the binding between NST and its analogues with proteins. These methods can also be used for other purposes such as radiation sterilization or determining pharmaceutical dosage.

Formula: C₅H₈N₄O₃S₂

Purity: Min. 95%

Molecular weight: 236.3 g/mol

Ref: 3D-AAA09875