CAS 98-92-0

Nicotinamide

Description:

Nicotinamide, also known as niacinamide, is an amide form of vitamin B3 and is characterized by its white crystalline appearance. It is soluble in water and alcohol, making it readily bioavailable for various applications. This compound plays a crucial role in cellular metabolism as a precursor to nicotinamide adenine dinucleotide (NAD+), which is essential for energy production and enzymatic reactions in the body. Nicotinamide exhibits anti-inflammatory properties and is often used in dermatological formulations to improve skin barrier function, reduce acne, and diminish signs of aging. Additionally, it has been studied for its potential neuroprotective effects and role in preventing certain diseases. The substance is generally recognized as safe for topical and oral use, although high doses may lead to side effects. Its versatility extends to the pharmaceutical and cosmetic industries, where it is valued for its beneficial effects on skin health and overall metabolic function.

Formula: C₆H₆N₂O

InChI: InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key: InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

SMILES: C(N)(=O)C=1C=CC=NC1

Synonyms:

• 3-(Aminocarbonyl)pyridine
• 3-Amidopyridine
• 3-Carbamoylpyridine
• 3-Pyridinecarboxylic acid amide
• Aminicotin
• Benicot
• Delonin Amide
• Dipegyl
• NAM
• Niacinamide
• Niavit PP
• Nicamina
• Nicamindon
• Nicasir
• Nicobion
• Nicofort
• Nicosan 2
• Nicosylamide
• Nicotilamide
• Nicotinamid
• Nicotinamida
• Nicotinamide
• Nicotine acid amide
• Nicotinic acid amide
• Nicotinic amide
• Nicotylamide
• Nicovit
• Nicovitina
• Nictoamide
• Niocinamide
• Niozymin
• Nsc 13128
• Nsc 27452
• Papulex
• Pelmin
• Pelmine
• Pelonin amide
• Pyridine-3-Carboxamide
• Vi-Nicotyl
• Vitamin B
• Vitamin B3
• Vitamin B₃ (niacinamide)
• Vitamin B₃ (nicotinamide)
• m-(Aminocarbonyl)pyridine
• β-Pyridinecarboxamide
• Vitamin PP
• VPP
• 3-Pyridinecarboxyamide
• Pyridine-3-Carboxyamide
• 3-Pyridinecarboxamide
• niacinamide cell culture tested
• Nicotinamide (1.06818)
• PYRIDINE-3-CARBOXYLIC ACID AMIDE
• Amide PP
• NICETHAMIDUM
• 3-PYRIDINECARBOXYLIC AMIDE
• acidamide
• -(Aminocarbonyl)pyridine
• Amid kyseliny nikotinove
• 3-PYRIDINE CARBOXYLIC ACID AMIDE
• VITAMIN B3/B5
• TIMTEC-BB SBB004283

Nicotinamide RS

CAS: 98-92-0

Color and Shape: White

Ref: 2K-1103000021

Nicotinamide

Controlled Product

CAS: 98-92-0

Applications A water-soluble vitamin B, incorporated within nicotinamide cofactors such as NADH and NADPH.
References Sharma, M., et al.: J. Chem. Pharm. Res., 2, 416 (2010), Al-Nadaf, A., et al.: Bioorg. Medi. Chem., 18, 3088 (2010),

Formula: C₆H₆N₂O

Color and Shape: Neat

Molecular weight: 122.12

Ref: TR-N407750

Niacinamide

CAS: 98-92-0

Vitamin B3; antioxidant; favours cell repair

Formula: C₆H₆N₂O

Purity: 98.5 To 101.5 Area-%

Color and Shape: White Powder

Molecular weight: 122.12 g/mol

Ref: 3D-FN01411

Nicotinamide - Bio-X ™

CAS: 98-92-0

Nicotinamide is a form of vitamin B that is found in food and it used to treat many conditions such as pellagra and acne. It replenishes cellular energy and has anti-inflammatory effects. Nicotinamide is an inhibitor of the enzyme SIRT1 in vitro but can be a stimulator in cells.

Formula: C₆H₆N₂O

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 122.12 g/mol

Ref: 3D-BN166252

Nicotinamide for cell culture, 99.5%, Endotoxin (BET) 0.05EU/mg

CAS: 98-92-0

Formula: C₆H₆N₂O

Purity: min. 99.5%

Color and Shape: White, Crystalline powder

Molecular weight: 122.13

Ref: SR-93517

Nicotinamide extrapure, 99.5%

CAS: 98-92-0

Formula: C₆H₆N₂O

Purity: min. 99.5%

Color and Shape: White, Crystalline powder

Molecular weight: 122.13

Ref: SR-72860

Nicotinamide-13C6

Controlled Product

CAS: 98-92-0

Formula: C₆H₆N₂O

Color and Shape: Neat

Molecular weight: 128.0806

Ref: TR-N407754

Nicotinamide-13C6

CAS: 98-92-0

Nicotinamide-13C6 is an isotopically labeled compound, which is a stable isotope variant of the naturally occurring nicotinamide. This compound is synthesized through advanced chemical processes that incorporate six carbon-13 isotopes, replacing the common carbon-12 atoms. The mode of action involves its integration into biological systems, where it serves as a tracer for metabolic studies and elucidates nicotinamide metabolism pathways with high precision.

Formula: C₆H₆N₂O

Purity: Min. 95%

Molecular weight: 128.08 g/mol

Ref: 3D-BN183763

Nicotinamide

CAS: 98-92-0

Nicotinamide is an amide form of vitamin B3, which is a water-soluble vitamin derived from dietary sources such as meat, fish, and yeast. In cellular biology, it functions as a precursor to nicotinamide adenine dinucleotide (NAD+), a critical coenzyme in redox reactions and energy production within the cells. Nicotinamide facilitates the transfer of electrons in metabolic processes, contributing to ATP production and cellular respiration. Moreover, it plays a pivotal role in DNA repair and cellular signaling through the regulation of sirtuins and poly(ADP-ribose) polymerases (PARPs).

Formula: C₆H₆N₂O

Purity: Min. 97.0 Area-%

Molecular weight: 122.12 g/mol

Ref: 3D-Q-201470