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CAS 980-71-2

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(±)-Brompheniramine maleate

Description:
(±)-Brompheniramine maleate is an antihistamine used primarily for the relief of allergy symptoms, such as runny nose, sneezing, and itching. It is a salt formed from brompheniramine, a first-generation antihistamine, and maleic acid. This compound exhibits anticholinergic properties, which can lead to side effects such as drowsiness, dry mouth, and blurred vision. As a racemic mixture, it contains equal parts of both enantiomers, contributing to its pharmacological effects. The substance is typically administered orally and is often found in combination with other medications to enhance its efficacy. In terms of physical characteristics, (±)-Brompheniramine maleate is usually presented as a white to off-white crystalline powder, soluble in water and alcohol. Its chemical structure includes a phenyl ring and a bromine atom, which are integral to its activity as an antihistamine. Safety and efficacy profiles are well-documented, but caution is advised in patients with certain medical conditions or those taking specific medications due to potential interactions.
Formula:C16H19BrN2·C4H4O4
InChI:InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key:InChIKey=SRGKFVAASLQVBO-BTJKTKAUSA-N
SMILES:C(=C\C(O)=O)\C(O)=O.C(CCN(C)C)(C1=CC=C(Br)C=C1)C2=CC=CC=N2
Synonyms:
  • 2-(P-Bromo-Alpha-(2-(Dimethylamino)Ethyl)Benzyl)-Pyridinmaleate(1:1)
  • 2-(P-Bromo-Alpha-(2-(Dimethylamino)Ethyl)Benzyl)Pyridinemaleate(1:1)
  • 2-Pyridinepropanamine, γ-(4-bromophenyl)-N,N-dimethyl-, (2Z)-2-butenedioate (1:1)
  • 2-Pyridinepropanamine, γ-(4-bromophenyl)-N,N-dimethyl-, (Z)-2-butenedioate (1:1)
  • 2-[p-Bromo-α-(2-dimethylaminoethyl)benzyl]pyridine maleate
  • 2-[p-Bromo-α-[2-(dimethylamino)ethyl]benzyl]pyridine bimaleate
  • 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine (2Z)-but-2-enedioate
  • Allent
  • Bromopheniramine maleate
  • Brompheniramine Maleate
  • See more synonyms
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