CAS 98049-69-5
:Lipoxin B4
Description:
Lipoxin B4 (LXB4) is a bioactive lipid mediator that plays a crucial role in the resolution of inflammation. It is a member of the lipoxin family, which are derived from arachidonic acid through the action of lipoxygenases. LXB4 is characterized by its structure, which includes a hydroxyl group and multiple double bonds, contributing to its biological activity. This compound is known for its anti-inflammatory properties, promoting the resolution of inflammation by inhibiting neutrophil recruitment and enhancing the clearance of apoptotic cells. Lipoxin B4 interacts with specific receptors, such as the ALX/FPR2 receptor, mediating various cellular responses. It is also involved in processes such as tissue repair and modulation of immune responses. Due to its significant role in inflammation and immune regulation, LXB4 has garnered interest in therapeutic applications, particularly in conditions characterized by chronic inflammation. Its stability and bioavailability are important factors in its potential use in clinical settings.
Formula:C20H32O5
InChI:InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1
InChI key:InChIKey=UXVRTOKOJOMENI-WLPVFMORSA-N
SMILES:[C@H]([C@H](CCCCC)O)(/C=C/C=C/C=C\C=C\[C@H](CCCC(O)=O)O)O
Synonyms:- (5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxy-6,8,10,12-eicosatetraenoic acid
- 5S,14R,15S-Trihydroxy-6,10,12-trans-8-cis-eicosatetraenoic acid
- 6,8,10,12-Eicosatetraenoic acid, 5,14,15-trihydroxy-, (5S,6E,8Z,10E,12E,14R,15S)-
- 6,8,10,12-Eicosatetraenoic acid, 5,14,15-trihydroxy-, [5S-(5R*,6E,8Z,10E,12E,14S*,15R*)]-
- 98049-69-5
- LXB<sub>4</sub>
- Lipoxin B<sub>4</sub>
- Lipoxin B4
- LXB4
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Lipoxin B4
CAS:Lipoxin B4 is a metabolite of arachidonic acid that inhibits leukocyte infiltration and mucus secretion in the nasal mucosa of the upper respiratory tract.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.47
