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CAS 98072-47-0

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Hemolysins O, Streptococcus group A

Description:
Hemolysin O, produced by Streptococcus pyogenes (Group A Streptococcus), is a pore-forming toxin that plays a significant role in the pathogenicity of this bacterium. It is a protein that exhibits hemolytic activity, meaning it can lyse red blood cells, leading to the release of hemoglobin. This characteristic is crucial for the bacterium's ability to evade the host's immune response and establish infection. Hemolysin O operates by inserting itself into the lipid bilayer of cell membranes, forming pores that disrupt cellular integrity and function. The toxin is also involved in the inflammatory response, contributing to tissue damage and the symptoms associated with streptococcal infections. Its activity is influenced by various factors, including the presence of specific ions and the local environment. Understanding the properties and mechanisms of Hemolysin O is essential for developing therapeutic strategies against infections caused by Streptococcus pyogenes.
Formula:Unspecified
Synonyms:
  • Hemolysins O, Streptococcus group A
  • streptolysin O from streptococcus*pyogenes
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