CAS 98084-68-5

Atriopeptin I, also known as Atrial Natriuretic Peptide (ANP), is a peptide hormone primarily produced in the atria of the heart. It plays a crucial role in regulating blood pressure and fluid balance in the body. The substance is characterized by its ability to induce natriuresis, which is the excretion of sodium through urine, and it also promotes vasodilation, leading to a decrease in blood volume and pressure. Atriopeptin I is composed of a chain of amino acids, typically consisting of 28 residues, and is classified as a member of the natriuretic peptide family. Its synthesis is stimulated by atrial stretch, which occurs in response to increased blood volume. The hormone acts on various target organs, including the kidneys and blood vessels, by binding to specific receptors, thereby initiating a cascade of intracellular signaling pathways. Due to its physiological effects, Atriopeptin I is of interest in cardiovascular research and potential therapeutic applications for conditions such as hypertension and heart failure.