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CAS 98185-20-7

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Raclopride tartrate

Description:
Raclopride tartrate is a chemical compound primarily recognized as a selective antagonist for dopamine D2 receptors, making it significant in pharmacological research, particularly in the study of neuropsychiatric disorders. It is often utilized in animal studies to investigate the effects of dopamine modulation. The compound is a salt formed from raclopride and tartaric acid, which enhances its solubility and stability. Raclopride itself is a bicyclic compound, and its structure contributes to its binding affinity for dopamine receptors. The tartrate form is typically more soluble in aqueous solutions, facilitating its use in various experimental settings. In terms of physical properties, raclopride tartrate is usually a white to off-white crystalline powder. It is important to handle this compound with care, as it may have specific safety and toxicity considerations. Overall, raclopride tartrate serves as a valuable tool in neuroscience research, particularly in understanding the role of dopamine in behavior and mental health.
Formula:C15H20Cl2N2O3·C4H6O6
InChI:InChI=1S/C15H20Cl2N2O3.C4H6O6/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2;5-1(3(7)8)2(6)4(9)10/h7,9,20H,3-6,8H2,1-2H3,(H,18,21);1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
InChI key:InChIKey=QULBVRZTKPQGCR-NDAAPVSOSA-N
SMILES:C(NC[C@H]1N(CC)CCC1)(=O)C2=C(OC)C(Cl)=CC(Cl)=C2O.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O
Synonyms:
  • Benzamide, 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxy-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
  • Raclopride (+)-tartrate
  • Benzamide, 3,5-dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxy-, (S)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)
  • Raclopride tartrate
  • Benzamide, 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxy-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
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