CAS 982-24-1

Clopenthixol

Description:

Clopenthixol is an antipsychotic medication belonging to the thioxanthene class, primarily used in the treatment of schizophrenia and other psychotic disorders. It functions as a dopamine antagonist, primarily blocking D2 receptors in the brain, which helps to alleviate symptoms such as hallucinations and delusions. Clopenthixol exhibits a combination of both sedative and antipsychotic properties, making it effective in managing acute episodes of psychosis as well as providing long-term stabilization. The substance is typically administered in the form of its hydrochloride salt, which enhances its solubility and bioavailability. Clopenthixol can be delivered orally or via intramuscular injection, with the latter often used for patients requiring rapid control of symptoms. Common side effects may include sedation, extrapyramidal symptoms, and weight gain, which are typical of many antipsychotic medications. Due to its pharmacological profile, clopenthixol is often prescribed with caution, considering the potential for adverse effects and the need for regular monitoring of the patient's response to treatment.

Formula: C₂₂H₂₅ClN₂OS

InChI: InChI=1S/C22H25ClN2OS/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26/h1-2,4-8,16,26H,3,9-15H2

InChI key: InChIKey=WFPIAZLQTJBIFN-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CCO)CC1)=C2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3

Synonyms:

• 1-Piperazineethanol, 4-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-
• 1-Piperazineethanol, 4-(3-(2-chlorothioxanthen-9-ylidene)propyl)-
• 2-(4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol
• 2-(4-[3-(2-Chloro-9-thioxanthenylidene)propyl]-1-piperazinyl)ethanol
• 4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol
• 4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol
• 9H-Thioxanthene, 1-piperazineethanol deriv.
• Ay 62021
• Chlorpenthixol
• Clopenthixol [USAN:INN:BAN]
• Clopenthixolum
• Clopenthixolum [INN-Latin]
• Clopentixol
• Clopentixol [INN-Spanish]
• Nsc 64087
• Sordinol

trans-Clopenthixol

CAS: 982-24-1

Formula: C₂₂H₂₅ClN₂OS

Molecular weight: 400.9647

Ref: IN-DA00IK1W

Zuclopenthixol (Clopenthixol) (Mixture of Z and E Isomers)

CAS: 982-24-1

Formula: C₂₂H₂₅ClN₂OS

Color and Shape: Off-White Solid

Molecular weight: 400.97

Ref: 4Z-Z-101

Clopenthixol

CAS: 982-24-1

Formula: C₂₂H₂₅ClN₂OS

Molecular weight: 400.96

Ref: 7W-GP9700

Clopenthixol

Controlled Product

CAS: 982-24-1

Clopenthixol is a medicinal compound that acts as a protein kinase inhibitor, blocking the activity of enzymes that regulate cell growth and division. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in animal models. Clopenthixol is also an inhibitor of chitin synthesis, which is important for the structural integrity of fungal cell walls. This compound has been detected in urine samples from Chinese individuals and may have potential as an anticancer agent. Additionally, clopenthixol has been found to bind to heparin, a glycosaminoglycan involved in blood clotting and inflammation. Its unique properties make it a promising candidate for further research into potential therapeutic applications.

Formula: C₂₂H₂₅ClN₂OS

Purity: Min. 95%

Molecular weight: 401 g/mol

Ref: 3D-AAA98224

Clopenthixol

CAS: 982-24-1

Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

Formula: C₂₂H₂₅ClN₂OS

Color and Shape: Solid

Molecular weight: 400.96

Ref: TM-T68193