CAS 98556-31-1

4-chloro-6-iodoquinazoline

Description:

4-Chloro-6-iodoquinazoline is a heterocyclic organic compound characterized by its quinazoline core, which consists of a fused benzene and pyrimidine ring. The presence of chlorine and iodine substituents at the 4 and 6 positions, respectively, contributes to its unique chemical properties and reactivity. This compound typically appears as a solid at room temperature and is often used in medicinal chemistry and research due to its potential biological activity. The halogen substituents can influence the compound's lipophilicity, solubility, and interaction with biological targets, making it of interest in drug development. Additionally, 4-chloro-6-iodoquinazoline may exhibit specific spectral characteristics in techniques such as NMR and IR spectroscopy, which can be utilized for its identification and characterization. Safety data should be consulted, as halogenated compounds can pose health risks, and proper handling and disposal procedures should be followed in laboratory settings.

Formula: C₈H₄ClIN₂

InChI: InChI=1/C8H4ClIN2/c9-8-6-3-5(10)1-2-7(6)11-4-12-8/h1-4H

SMILES: c1cc2c(cc1I)c(Cl)ncn2

Synonyms:

• 4-Chloro-6-iodo-quinazoline
• 6-Iodo-4-chloroquinazoline
• 4-CHLORO-6-IODOQUINAZOLINE

Quinazoline, 4-chloro-6-iodo-

CAS: 98556-31-1

Formula: C₈H₄ClIN₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 290.4882

Ref: IN-DA00IK4R

4-Chloro-6-iodoquinazoline

CAS: 98556-31-1

4-Chloro-6-iodoquinazoline

Purity: 98%

Color and Shape: Yellow Solid

Molecular weight: 290.49g/mol

Ref: 54-OR30701

4-Chloro-6-iodoquinazoline

Controlled Product

CAS: 98556-31-1

Applications 4-Chloro-6-iodoquinazoline is an intermediate in the synthesis of Lapatinib (L175800).
References Petrov, K., et al.: Bioorg. Med. Chem. Lett., 16, 4686 (2006),

Formula: C₈H₄ClIN₂

Color and Shape: Neat

Molecular weight: 290.49

Ref: TR-C367295

4-Chloro-6-iodoquinazoline

CAS: 98556-31-1

Formula: C₈H₄ClIN₂

Purity: >98.0%(GC)

Color and Shape: White to Yellow to Green powder to crystal

Molecular weight: 290.49

Ref: 3B-C2775

4-Chloro-6-iodoquinazoline

CAS: 98556-31-1

4-Chloro-6-iodoquinazoline is a synthetic molecule that binds to the tyrosine kinase domain of trifluoroacetic acid polymerase chain (TFPPC) and inhibits its activity. 4-Chloro-6-iodoquinazoline has been shown to have antifilarial and anti-cancer properties. In addition, it has been shown to be an effective inhibitor of epidermal growth factor (EGF), which is a potent mitogen for cells in culture. In clinical studies, 4-chloro-6-iodoquinazoline has been shown to be safe for use in humans.

Formula: C₈H₄ClIN₂

Purity: Min. 95%

Molecular weight: 290.49 g/mol

Ref: 3D-FC32925

4-Chloro-6-iodoquinazoline

CAS: 98556-31-1

Formula: C₈H₄ClIN₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 290.49

Ref: 10-F067584