CAS 98625-26-4

(-)-(S)-Bay K 8644

Description:

(-)-(S)-Bay K 8644 is a chemical compound classified as a dihydropyridine derivative, primarily known for its role as a selective calcium channel agonist. It is often utilized in pharmacological research to study calcium channel activity and its implications in various physiological processes. The compound exhibits stereochemistry, with the "S" designation indicating its specific spatial arrangement, which is crucial for its biological activity. As a calcium channel activator, Bay K 8644 enhances the influx of calcium ions into cells, influencing muscle contraction and neurotransmitter release. This compound is particularly relevant in cardiovascular research, where it helps in understanding the modulation of vascular smooth muscle tone and cardiac function. In terms of solubility, it is typically soluble in organic solvents, which facilitates its use in laboratory settings. Safety and handling precautions are essential, as with many chemical substances, to mitigate any potential hazards associated with its use. Overall, (-)-(S)-Bay K 8644 serves as a valuable tool in the exploration of calcium signaling pathways in various biological systems.

Formula: C₁₆H₁₅F₃N₂O₄

InChI: InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1

InChI key: InChIKey=ZFLWDHHVRRZMEI-ZDUSSCGKSA-N

SMILES: C(OC)(=O)C=1[C@@H](C(N(=O)=O)=C(C)NC1C)C2=C(C(F)(F)F)C=CC=C2

Synonyms:

• (-)-BAY-k 8644
• (-)-Bay R 5417
• (S)-Methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate
• 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methyl ester, (4S)-
• 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methyl ester, (S)-
• S-(-)-bay K8644
• methyl (4S)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
• (-)-(S)-Bay K 8644

(-)-(S)-Bay K 8644

CAS: 98625-26-4

Formula: C₁₆H₁₅F₃N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 356.2965

Ref: IN-DA01DOSD

(S)-(-)-Bay-K-8644

CAS: 98625-26-4

(S)-(-)-Bay-K-8644

Purity: ≥98%

Molecular weight: 356.3g/mol

Ref: 54-BUP00403

(S)-(-)-Bay K8644

CAS: 98625-26-4

Formula: C₁₆H₁₅F₃N₂O₄

Molecular weight: 356.30

Ref: 7W-GL8789

(S)-(-)-Bay K 8644

CAS: 98625-26-4

(S)-(-)-Bay K 8644

Purity: 98%

Molecular weight: 356.30g/mol

Ref: 54-BISN0033

(S)-(-)-Bay-K-8644

CAS: 98625-26-4

(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.

Formula: C₁₆H₁₅F₃N₂O₄

Purity: 98.28% - 99.37%

Color and Shape: Solid

Molecular weight: 356.3

Ref: TM-TQ0144