CAS 98665-19-1
:Ganoderic acid H
Description:
Ganoderic acid H is a triterpenoid compound primarily derived from the medicinal mushroom Ganoderma lucidum, commonly known as reishi or lingzhi. This compound is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and hepatoprotective effects. Ganoderic acid H exhibits a complex molecular structure characterized by multiple rings and functional groups, contributing to its biological activity. It is typically found in the fruiting bodies and mycelium of the mushroom, where it plays a role in the organism's defense mechanisms. The compound is soluble in organic solvents but has limited solubility in water, which can influence its bioavailability and therapeutic applications. Research into ganoderic acid H continues to explore its potential benefits in traditional medicine and modern pharmacology, particularly in the context of cancer treatment and immune system support. As with many natural compounds, further studies are necessary to fully understand its mechanisms of action and potential side effects.
Formula:C31H42O9
InChI:InChI=1/C32H44O9/c1-15(11-18(34)12-16(2)28(39)40)19-13-23(37)32(8)24-20(35)14-21-29(4,5)22(36)9-10-30(21,6)25(24)26(38)27(31(19,32)7)41-17(3)33/h15-16,19,21-22,27,36H,9-14H2,1-8H3,(H,39,40)/t15-,16+,19+,21-,22-,27+,30-,31-,32-/m0/s1
InChI key:InChIKey=YCXUCEXEMJPDRZ-UHFFFAOYSA-N
SMILES:CC12C(C)(C(OC(C)=O)C(=O)C3=C1C(=O)CC4C3(C)CCC(O)C4(C)C)C(C(CC(CC(C(O)=O)C)=O)C)CC2=O
Synonyms:- Ganoderic acid H
- Lanost-8-en-26-oic acid, 12-(acetyloxy)-3-hydroxy-7,11,15,23-tetraoxo-, (3β,12β)-
- (3β,12β)-12-(Acetyloxy)-3-hydroxy-7,11,15,23-tetraoxolanost-8-en-26-oic acid
- (3beta,12beta)-12-(acetyloxy)-3-hydroxy-7,11,15,23-tetraoxo- lanost-8-en-26-oic acid
- GANODERIC ACID H USP/EP/BP
- 12β-Acetyloxy-3β-hydroxy-7,11,15,23-tetraoxo-5α-lanost-8-en-26-oic acid
- Aids070762
- Aids-070762
- 12.beta.-Acetyloxy-3.beta.-hydroxy-7,11,15,23-tetraoxolanost-8-en-26-oic acid
- 12β-Acetoxy-3β-hydroxy-7,11,15,23-tetraoxo-5α-lanosta-8-ene-26-oic acid
- See more synonyms
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Found 5 products.
Ganoderic Acid H
CAS:Ganoderic acid H( GA-H )and ganoderic acid A(GA-A ) suppress growth (cell proliferation and colony formation) and invasive behavior (adhesion, migration and invasion) of MDA-MB-231 cells; they mediate their biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4 and the suppression of secretion of uPA, respectively; furthermore, the activity of ganoderic acids is linked to the hydroxylation in the position 7 and 15 (GA-A) and 3 (GA-H) in their triterpene lanostane structure; so hydroxylated triterpenes from G. lucidum could be promising natural agents for the therapy of invasive breast cancers.Formula:C32H44O9Purity:95%~99%Color and Shape:PowderMolecular weight:572.695Ganoderic acid H
CAS:Ganoderic acid H inhibits AP-1/NF-κB, suppressing uPA to exert antitumor effects.Formula:C32H44O9Purity:95% - 97.14%Color and Shape:SolidMolecular weight:572.69Ganoderic acid H
CAS:Controlled Product<p>Ganoderic acid H is a polyphenol found in the mushroom Ganoderma lucidum. It has been shown to induce autophagy, a process by which cells degrade their own components and recycle them. This molecule also inhibits cancer cell growth in vitro and in vivo, as well as surface methodology. The effective dose of ganoderic acid H is unknown, but it has been shown to be effective at concentrations of 10-100 μM for inhibiting the growth of human liver cancer cells. Other studies have shown that this polyphenol inhibits enzymes such as acetylcholinesterase, proteases, and lipases.</p>Formula:C32H44O9Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:572.69 g/mol
