CAS 98791-67-4

methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate

Description:

Methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate, with CAS number 98791-67-4, is a chemical compound belonging to the class of dihydropyridines, which are known for their role in pharmacology, particularly as calcium channel blockers. This compound features a dihydropyridine core substituted with a nitro group and a trifluoromethylphenyl moiety, contributing to its unique chemical properties. The presence of the methyl ester functional group enhances its lipophilicity, potentially influencing its bioavailability and pharmacokinetics. The chirality at the 4-position of the dihydropyridine ring indicates that it may exhibit stereoselective behavior in biological systems. Additionally, the trifluoromethyl group is known to enhance metabolic stability and can affect the compound's interaction with biological targets. Overall, this compound's structural features suggest potential applications in medicinal chemistry, particularly in the development of cardiovascular agents or other therapeutic applications.

Formula: C₁₆H₁₅F₃N₂O₄

InChI: InChI=1/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m1/s1

SMILES: CC1=C([C@@H](c2ccccc2C(F)(F)F)C(=C(C)N1)N(=O)=O)C(=O)OC

Synonyms:

• 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methyl ester, (4R)-
• Methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate

3-Pyridinecarboxylic acid,1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-, methylester, (4R)-

CAS: 98791-67-4

Formula: C₁₆H₁₅F₃N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 356.2965

Ref: IN-DA01DOSP

Methyl (R)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate

CAS: 98791-67-4

Methyl (R)-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate

Purity: 98%

Molecular weight: 356.3g/mol

Ref: 54-PC1006501

(R)-(+)-Bay-K-8644

CAS: 98791-67-4

(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.

Formula: C₁₆H₁₅F₃N₂O₄

Purity: 96.51% - 96.51%

Color and Shape: Solid

Molecular weight: 356.3

Ref: TM-TQ0145