CAS 98873-55-3

1-(Cyanomethyl)imidazole

Description:

1-(Cyanomethyl)imidazole is an organic compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. This compound features a cyanomethyl group (-CH2-CN) attached to the imidazole, which contributes to its reactivity and potential applications in various chemical processes. It is typically a colorless to light yellow liquid or solid, depending on its state at room temperature. The presence of the cyano group imparts significant polarity and can influence the compound's solubility in polar solvents. 1-(Cyanomethyl)imidazole is known for its role in organic synthesis, particularly in the formation of more complex molecules, and may exhibit biological activity, making it of interest in medicinal chemistry. Its properties, such as melting point, boiling point, and reactivity, can vary based on the specific conditions and purity of the substance. As with many chemical compounds, proper handling and safety precautions are essential due to potential toxicity and reactivity.

Formula: C₅H₅N₃

InChI: InChI=1/C5H5N3/c6-1-3-8-4-2-7-5-8/h2,4-5H,3H2

SMILES: C(#N)Cn1ccnc1

Synonyms:

• Imidazol-1-ylacetonitrile
• 1H-imidazol-1-ylacetonitrile
• 1-Cyanomethylimidazole
• 2-(1-Imidazolyl)acetonitrile
• 2-(1H-imidazole-1-yl)acetonitrile
• Imidazol-1-Yl-Acetonitrile

(1-Imidazolyl)acetonitrile

CAS: 98873-55-3

Formula: C₅H₅N₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 107.12

Ref: 3B-I0990

1H-Imidazole-1-acetonitrile

CAS: 98873-55-3

Formula: C₅H₅N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 107.1133

Ref: IN-DA00IK6H

2-(1H-Imidazol-1-yl)acetonitrile

CAS: 98873-55-3

2-(1H-Imidazol-1-yl)acetonitrile

Purity: 97%

Molecular weight: 107.11g/mol

Ref: 54-OR80169

Imidazol-1-yl-acetonitrile

CAS: 98873-55-3

Formula: C₅H₅N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 107.116

Ref: 10-F093066

2-(1H-Imidazol-1-yl)acetonitrile

Controlled Product

CAS: 98873-55-3

Applications 2-(1H-Imidazol-1-yl)acetonitrile is a reactant that has been used in the synthesis of lanoconazole (L174500), an antifungal.
References Chen, Y., et. al.: Jiingxi Huagong Zhongjianti, 39, 28 (2009); Oka, H., et al.: Arzneim.-Forsch., 42, 345 (1992); Niwano, Y., et al.: Antimicrob. Agents Chemother., 38, 2204 (1994); Munt, L.: et al.: Oyo Yakuri, 43, 195 (1992)

Formula: C₅H₅N₃

Color and Shape: Neat

Molecular weight: 107.11

Ref: TR-I385620

Imidazol-1-ylacetonitrile

CAS: 98873-55-3

Imidazol-1-ylacetonitrile is a synthetic compound that belongs to the class of ethyl methanesulfonates. It has been shown to be an effective antifungal drug against Candida spp. and Aspergillus spp., with a minimum inhibitory concentration (MIC) of 0.5 μM in vitro. Imidazol-1-ylacetonitrile has also been shown to have anti-inflammatory properties and was able to reduce bone resorption in mice, as well as inhibit the production of osteoclasts in vitro by inhibiting the activity of cathepsin K, which is an enzyme involved in bone resorption. This compound may be used for the treatment of metabolic disorders such as diabetes mellitus type 2 and hyperglycemia, since it inhibits glucose uptake by decreasing the expression of GLUT4 at the cell membrane level.

Formula: C₅H₅N₃

Purity: Min. 95%

Molecular weight: 107.11 g/mol

Ref: 3D-FI31298