CAS 98897-14-4

N-(hydroxymethyl)adenosine

Description:

N-(hydroxymethyl)adenosine is a modified nucleoside that features an adenosine backbone with a hydroxymethyl group attached to the nitrogen atom at the 6-position. This structural modification can influence its biochemical properties and interactions. The compound is known to play a role in various biological processes, particularly in the context of cellular signaling and metabolism. It may exhibit unique pharmacological properties, making it of interest in research related to nucleoside analogs and their potential therapeutic applications. The presence of the hydroxymethyl group can enhance solubility and stability compared to unmodified nucleosides. Additionally, N-(hydroxymethyl)adenosine can participate in hydrogen bonding and other interactions that may affect its binding affinity to enzymes or receptors. Its CAS number, 98897-14-4, is a unique identifier that facilitates the cataloging and retrieval of information regarding this compound in chemical databases. Overall, N-(hydroxymethyl)adenosine represents a significant area of study in medicinal chemistry and biochemistry due to its potential implications in drug development and cellular function.

Formula: C₁₁H₁₅N₅O₅

InChI: InChI=1/C11H15N5O5/c17-1-5-7(19)8(20)11(21-5)16-3-14-6-9(15-4-18)12-2-13-10(6)16/h2-3,5,7-8,11,17-20H,1,4H2,(H,12,13,15)/t5-,7-,8-,11-/m1/s1

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c(ncnc23)NCO)O1)O)O)O

Synonyms:

• adenosine, N-(hydroxymethyl)-

N6-(Hydroxymethyl)adenosine (~90%)

CAS: 98897-14-4

Applications N6-(Hydroxymethyl)adenosine is an intermediate with modified ribonucleoside formed by chemical oxidation of N6-methyladenosine (M275895) mediated by bicarbonate-activated hydrogen peroxide. N6-(Hydroxymethyl)adenosine is also reported as active mutagen.
References Alderson, T.: Mutat. Res-Rev. Genet., 154, 101 (1985); Wu, J., et al.: Chem. Sci., 6, 3013 (2015);

Formula: C₁₁H₁₅N₅O₅

Purity: ~90%

Color and Shape: Neat

Molecular weight: 297.27

Ref: TR-H805075

N6-Hydroxymethyladenosine

CAS: 98897-14-4

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Formula: C₁₁H₁₅N₅O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 297.27 g/mol

Ref: 3D-NH178111