CAS 98929-98-7

N(alpha),N(im)-di-fmoc-L-histidine

Description:

N(alpha),N(im)-di-fmoc-L-histidine is a protected derivative of the amino acid histidine, commonly used in peptide synthesis and bioconjugation applications. The "fmoc" (9-fluorenylmethoxycarbonyl) groups serve as protective groups for the amino functionalities, allowing for selective deprotection during synthesis. This compound retains the essential characteristics of histidine, including its imidazole side chain, which can participate in various chemical reactions and interactions, such as metal coordination and hydrogen bonding. The presence of the two fmoc groups enhances the stability and solubility of the compound in organic solvents, making it suitable for solid-phase peptide synthesis. Additionally, the compound's structure allows for easy cleavage of the fmoc groups under mild basic conditions, facilitating the release of the free amino acid or peptide. Overall, N(alpha),N(im)-di-fmoc-L-histidine is a valuable intermediate in the synthesis of biologically active peptides and proteins, contributing to advancements in medicinal chemistry and drug development.

Formula: C₃₆H₂₉N₃O₆

InChI: InChI=1/C36H29N3O6/c40-34(41)33(38-35(42)44-19-31-27-13-5-1-9-23(27)24-10-2-6-14-28(24)31)17-22-18-37-21-39(22)36(43)45-20-32-29-15-7-3-11-25(29)26-12-4-8-16-30(26)32/h1-16,18,21,31-33H,17,19-20H2,(H,38,42)(H,40,41)/t33-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](Cc1cncn1C(=O)OCC1c2ccccc2c2ccccc12)C(=O)O)O

Synonyms:

• Fmoc-His(Fmoc)-OH
• N,3-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine
• N-α,N-im-di-Fmoc-L-histidine
• N,1-Bis-Fmoc-L-histidine
• N,N'-Bis(9-Fluorenylmethyloxycarbonyl)-L-Histidine

Fmoc-His(Fmoc)-OH

CAS: 98929-98-7

Formula: C₃₆H₂₉N₃O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 599.6320

Ref: IN-DA0066L6

N,N'-Bis(9-Fluorenylmethyloxycarbonyl)-L-Histidine

CAS: 98929-98-7

N,N'-Bis(9-Fluorenylmethyloxycarbonyl)-L-Histidine

Purity: 98%,100%ee

Molecular weight: 599.64g/mol

Ref: 54-OR1014107

Fmoc-His(Fmoc)-OH

CAS: 98929-98-7

Ref: 7W-GM1476

N-α,im-Bis-Fmoc-L-histidine

CAS: 98929-98-7

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Formula: C₃₆H₂₉N₃O₆

Purity: Min. 95%

Molecular weight: 599.63 g/mol

Ref: 3D-FI47733

Fmoc-His(Fmoc)-OH

CAS: 98929-98-7

M03416 - Fmoc-His(Fmoc)-OH

Formula: C₃₆H₂₉N₃O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 599.643

Ref: 10-M03416