CAS 99-45-6

Adrenalone

Description:

Adrenalone, also known as 3-hydroxy-1,2,3,4-tetrahydro-1-naphthalenyl-ethanone, is a synthetic compound that is structurally related to catecholamines, particularly adrenaline. It is characterized by its ketone functional group and a hydroxyl group, which contribute to its reactivity and biological activity. Adrenalone is typically a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. The compound is known for its potential pharmacological effects, including its influence on the cardiovascular system, where it may act as a sympathomimetic agent. Its chemical properties allow it to interact with adrenergic receptors, mimicking the effects of natural catecholamines. Due to its structural similarity to adrenaline, adrenalone may also exhibit various physiological effects, including increased heart rate and blood pressure. However, its use in clinical settings is limited, and it is primarily of interest in research contexts. Safety and handling precautions are essential when working with this compound, as with many chemicals that can have significant biological effects.

Formula: C₉H₁₁NO₃

InChI: InChI=1S/C9H11NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,10-12H,5H2,1H3

InChI key: InChIKey=PZMVOUYYNKPMSI-UHFFFAOYSA-N

SMILES: C(CNC)(=O)C1=CC(O)=C(O)C=C1

Synonyms:

• 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethan-1-one
• 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanone
• 3,4-Dihydroxy-2-(Methylamino)Acetophenone
• 3,4-Dihydroxy-α-methylaminoacetophenone
• 4-(Methylaminoacetyl)Catechol
• 4-Methylaminoacetopyrocatechol
• Acetophenone, 3′,4′-dihydroxy-2-(methylamino)-
• Adrenolone
• Adrenon
• Adrenone
• Chemosan
• Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)-
• Haemodan
• Kephrine
• Ketogaze
• Methaminoacetocatechol
• NSC 243611
• Stryphnon
• Stryphnone
• Styphnone
• Stypnon
• Stypnone
• U 2134

Adrenaline impurity standard

CAS: 26405-77-6, 51-41-2, 51-42-3, 54-06-8, 99-45-6

Adrenaline impurity standard

Color and Shape: Light Blue

Ref: 47-1251

1-(3,4-dihydroxyphenyl)-2-(methylamino)ethan-1-one

CAS: 99-45-6

Formula: C₉H₁₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.1885

Ref: IN-DA005SBB

Adrenalone

CAS: 99-45-6

Applications Adrenalone is a ketone derivative of Epinephrine (E588585) and a potential dopamine β oxidase inhibitor.
References Goldstein, M., et al.: Nature, 192, 1081 (1961)

Formula: C₉H₁₁NO₃

Color and Shape: Neat

Molecular weight: 181.19

Ref: TR-A305095

Adrenalone

Controlled Product

CAS: 99-45-6

Adrenalone is a caffeic acid derivative that contains a hydroxyl group. It is used in the treatment of infectious diseases, bowel disease, and autoimmune diseases. Adrenalone inhibits bacterial growth by interfering with cell wall synthesis, which prevents the formation of new cell walls and leads to bacterial death. It also inhibits the production of dopamine by acting on an amine oxidase enzyme. This drug has been shown to be effective in treating inflammatory bowel disease (IBD) in both mice and humans due to its ability to inhibit pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Formula: C₉H₁₁NO₃

Purity: Min. 95%

Color and Shape: Colourless To Pale Yellow Solid

Molecular weight: 181.19 g/mol

Ref: 3D-FA51364