CAS 99-81-0

4-Nitrophenacyl bromide

Description:

4-Nitrophenacyl bromide is an organic compound characterized by its aromatic structure, featuring a nitro group and a bromide substituent. It is typically a yellow crystalline solid, known for its reactivity, particularly in nucleophilic substitution reactions. The presence of the nitro group enhances the electrophilicity of the carbonyl carbon, making it susceptible to attack by nucleophiles. This compound is often used as a reagent in organic synthesis, particularly in the preparation of various derivatives and in the study of reaction mechanisms. It is also utilized in the field of biochemistry for labeling and modifying biomolecules. 4-Nitrophenacyl bromide is soluble in organic solvents such as acetone and dichloromethane but has limited solubility in water. Safety precautions should be taken when handling this compound, as it can be harmful if inhaled or ingested, and it may cause skin and eye irritation. Proper storage in a cool, dry place away from light is recommended to maintain its stability.

Formula: C₈H₆BrNO₃

InChI: InChI=1/C8H6BrNO3/c9-5-8(11)6-1-3-7(4-2-6)10(12)13/h1-4H,5H2

InChI key: InChIKey=MBUPVGIGAMCMBT-UHFFFAOYSA-N

SMILES: C(CBr)(=O)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• 2-Bromo-1-(4-Nitrophenyl)Ethanone
• 2-Bromo-1-(4-nitrophenyl)ethan-1-one
• 2-Bromo-4'-Nitroacetophenone
• 2-Bromo-4-nitroacentophenone
• 2-Bromo-p-nitroacetophenone
• 4-Nitro-α-bromoacetophenone
• 4-Nitrophenacyl bromide
• 4′-Nitro-2-bromoacetophenone
• Acetophenone, 2-bromo-4′-nitro-
• Bromomethyl 4-nitrophenyl ketone
• Bromomethyl p-nitrophenyl ketone
• Ethanone, 2-bromo-1-(4-nitrophenyl)-
• NSC 9805
• p-Nitro-α-bromoacetophenone
• p-Nitrophenacyl bromide
• α-Bromo-p-nitroacetophenone
• ω-Bromo-4-nitroacetophenone
• ω-Bromo-p-nitroacetophenone
• α-Bromo-4-nitroacetophenone
• p-Nitro-alpha-bromoacetophenone
• OMEGA-BROMO-4-NITROACETOPHENONE
• Acetophenone, 2'-bromo-p-nitro-
• ASISCHEM D48949
• omega-Bromo-p-nitroacetophenone
• ALPHA-BROMO-P-NITROACETOPHENONE
• ALPHA-BROMO-4-NITROACETOPHENONE

2-Bromo-4'-nitroacetophenone

CAS: 99-81-0

Formula: C₈H₆BrNO₃

Purity: >98.0%(GC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 244.04

Ref: 3B-N0473

2-Bromo-4'-nitroacetophenone, 95%

CAS: 99-81-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₆BrNO₃

Purity: 95%

Color and Shape: White to cream or yellow, Crystals or powder or crystalline powder

Molecular weight: 244.04

Ref: 02-A15374

2-Bromo-4'-Nitroacetophenone

CAS: 99-81-0

Formula: C₈H₆BrNO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 244.0421

Ref: IN-DA003GOS

4-Nitrophenacyl bromide

CAS: 99-81-0

4-Nitrophenacyl bromide

Formula: C₈H₆BrNO₃

Purity: 98%

Color and Shape: off-white to faint yellow powder

Molecular weight: 244.04214g/mol

Ref: 54-OR24069

4''-Nitrophenacyl bromide

CAS: 99-81-0

Formula: C₈H₆BrNO₃

Molecular weight: 244.05

Ref: 7W-GK6338

4-Nitrophenacyl bromide

CAS: 99-81-0

Formula: C₈H₆BrNO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 244.044

Ref: 10-F018905

2-Bromo-4'-nitroacetophenone

CAS: 99-81-0

2-Bromo-4'-nitroacetophenone is a chemical compound that has been shown to be active in enzyme inhibition experiments. It has been found to inhibit the activity of histidine decarboxylase, which catalyzes the conversion of histidine to histamine, and uv absorption. 2-Bromo-4'-nitroacetophenone binds to the active site of P450 enzymes, inhibiting their catalytic activity. This compound also inhibits fatty acid oxidation by binding to fatty acid hydroxylase and hydrogen bonds with tyrosine residues in proteins. 2-Bromo-4'-nitroacetophenone is structurally similar to 2-bromoacetophenone, which has been shown to have antihistaminic properties.

Formula: C₈H₆BrNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 244.04 g/mol

Ref: 3D-FB30921