CAS 99009-20-8

Pyrazoloacridine

Description:

Pyrazoloacridine is a synthetic compound characterized by its unique structure, which combines elements of both pyrazole and acridine moieties. This compound is notable for its potential biological activity, particularly in the field of medicinal chemistry, where it has been investigated for its antitumor properties. Pyrazoloacridine exhibits a planar, aromatic structure that contributes to its ability to intercalate with DNA, potentially disrupting cellular processes in cancer cells. The compound's solubility and stability can vary depending on the solvent and conditions, which are important factors for its application in biological studies. Additionally, its pharmacological profile may include mechanisms of action such as inhibition of topoisomerases or induction of apoptosis in malignant cells. As with many synthetic compounds, further research is essential to fully understand its efficacy, safety, and potential therapeutic applications. Overall, pyrazoloacridine represents a promising area of study in the development of novel anticancer agents.

Formula: C₁₉H₂₁N₅O₃

InChI: InChI=1S/C19H21N5O3/c1-22(2)9-4-10-23-15-7-8-16(24(25)26)19-17(15)18(21-23)13-11-12(27-3)5-6-14(13)20-19/h5-8,11,20H,4,9-10H2,1-3H3

InChI key: InChIKey=HZCWPKGYTCJSEB-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C=3C(C=4C(N2)=CC=C(OC)C4)=NN(CCCN(C)C)C3C=C1

Synonyms:

• PZA
• NSC-366140
• 3-(9-methoxy-5-nitropyrazolo[3,4,5-kl]acridin-2(1H)-yl)-N,N-dimethylpropan-1-amine
• PD 115934
• NSC 366140
• Pyrazoloacridine
• Pyrazolo[3,4,5-kl]acridine-2(6H)-propanamine, 9-methoxy-N,N-dimethyl-5-nitro-
• 9-Methoxy-N,N-dimethyl-5-nitropyrazolo[3,4,5-kl]acridine-2(6H)-propanamine
• PD-115934
• 2-[3-(Dimethylamino)propyl]-9-methoxy-5-nitro-2,6-dihydropyrazolo[3,4,5-kl]acridine

Pyrazoloacridine

CAS: 99009-20-8

Pyrazoloacridine

Purity: ≥98%

Molecular weight: 367.4g/mol

Ref: 54-BUP03264

Pyrazoloacridine

CAS: 99009-20-8

Pyrazoloacridine is a ligand that binds to the receptor. It may be used as a research tool to study protein interactions and receptor function. Pyrazoloacridine is an inhibitor of ion channels, which are involved in the propagation of nerve impulses. The inhibition of ion channels leads to analgesic effects and anti-inflammatory activities. Pyrazoloacridine also inhibits the activity of peptides, such as vasopressin, which are involved in water balance, blood pressure regulation, and pain perception. Pyrazoloacridine is also an activator of high purity for peptides, such as vasopressin, which are involved in water balance, blood pressure regulation, and pain perception.

Formula: C₁₉H₂₁N₅O₃

Purity: Min. 95%

Molecular weight: 367.4 g/mol

Ref: 3D-ZDA00920

Pyrazoloacridine

CAS: 99009-20-8

Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.

Formula: C₁₉H₂₁N₅O₃

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 367.4

Ref: TM-T28475