CAS 99043-04-6

(3S,4S,6S)-3,4,5-trihydroxy-6-[(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoyl]oxy-tetrahydropyran-2-carboxylic acid

Description:

The chemical substance known as "(3S,4S,6S)-3,4,5-trihydroxy-6-[(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoyl]oxy-tetrahydropyran-2-carboxylic acid," with the CAS number 99043-04-6, is a complex organic compound characterized by its multiple hydroxyl groups and a tetrahydropyran ring structure. This compound features a carboxylic acid functional group, which contributes to its acidity and solubility in polar solvents. The presence of methoxy and hydroxy substituents indicates potential for hydrogen bonding, influencing its reactivity and interactions with biological systems. The isobenzofuran moiety suggests that it may exhibit interesting pharmacological properties, possibly acting as a bioactive compound. Its stereochemistry, indicated by the (3S,4S,6S) configuration, is crucial for its biological activity, as stereoisomers can have significantly different effects in biological systems. Overall, this compound's structural complexity and functional groups suggest potential applications in medicinal chemistry and biochemistry.

Formula: C₂₃H₂₈O₁₂

InChI: InChI=1/C23H28O12/c1-9(4-6-11-15(25)14-12(8-33-22(14)31)10(2)19(11)32-3)5-7-13(24)34-23-18(28)16(26)17(27)20(35-23)21(29)30/h4,16-18,20,23,25-28H,5-8H2,1-3H3,(H,29,30)/b9-4+/t16-,17-,18?,20?,23+/m0/s1

Mycophenolic Acid Acyl-β-D-glucuronide

CAS: 99043-04-6

Formula: C₂₃H₂₈O₁₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 496.4612

Ref: IN-DA0066FZ

Mycophenolic acid acyl-βeta-D-glucuronide

CAS: 99043-04-6

Mycophenolic acid acyl-βeta-D-glucuronide

Formula: C₂₃H₂₈O₁₂

Purity: >90%

Color and Shape: white amorphous solid

Molecular weight: 496.46g/mol

Ref: 54-BICL4132

Mycophenolic Acid Acyl Glucuronide (Mixture of Diastereomers)

CAS: 99043-04-6

Formula: C₂₃H₂₈O₁₂

Color and Shape: White To Off-White Solid

Molecular weight: 496.47

Ref: 4Z-M-167

Mycophenolic acid acyl-b-D-glucuronide

CAS: 99043-04-6

Ref: 7W-GC5220

Mycophenolic Acid Acyl-β-D-glucuronide

CAS: 99043-04-6

Stability Hygroscopic
Applications A metabolite of Mycophenolic Acid.
References Shipkova, M., et al.: Therap. Drug Monit., 24, 390 (2002), Picard, N., et al.: Drug Metab. Dispos., 33, 139 (2005),

Formula: C₂₃H₂₈O₁₂

Color and Shape: Neat

Molecular weight: 496.46

Ref: TR-M831525

Mycophenolic acid-D3 acyl-β-D-glucuronide (>90%)

Controlled Product

CAS: 99043-04-6

Applications A labelled metabolite of Mycophenolic Acid.
References Shipkova, M., et al.: Ther. Drug Monit., 24, 390 (2002), Picard, N., et al.: Drug Metab. Dispos., 33, 139 (2005),

Formula: C₂₃H₂₅D₃O₁₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 499.48

Ref: TR-M831527

Mycophenolic acid acyl-b-D-glucuronide

CAS: 99043-04-6

Mycophenolic acid acyl-b-D-glucuronide is a prodrug of mycophenolic acid that is metabolized by esterases to its active form. This compound has been shown to inhibit the activity of drug receptors, including those for immunosuppressants and anticonvulsants. Mycophenolic acid acyl-b-D-glucuronide has also been found to have a matrix effect on the concentration–time curve of other drugs in human serum. This drug is used for the treatment of bowel disease, autoimmune diseases, and for the prevention of organ transplant rejection. It can be administered orally or intravenously and has been shown to be well tolerated with few adverse effects.

Formula: C₂₃H₂₈O₁₂

Purity: Min. 90%

Color and Shape: Powder

Molecular weight: 496.47 g/mol

Ref: 3D-MM09680

Mycophenolic Acid Acyl Glucuronide

CAS: 99043-04-6

Formula: C₂₃H₂₈O₁₂

Molecular weight: 496.47

Ref: ST-EA-CP-M27032