CAS 99103-16-9

1-O-hexadecyl-2-acetyl-sn-glycero-3*phospho-(N,N,

Description:

1-O-Hexadecyl-2-acetyl-sn-glycero-3-phospho-(N,N) is a phospholipid derivative characterized by its long hydrophobic hexadecyl chain and an acetyl group at the second carbon of the glycerol backbone. This compound features a phosphate group that contributes to its amphiphilic nature, making it soluble in both aqueous and lipid environments. The presence of the hexadecyl chain enhances its membrane-forming capabilities, which is significant in biological systems, particularly in the formation of lipid bilayers. The acetyl group can influence the fluidity and stability of membranes, while the phospho-N,N moiety may play a role in interactions with proteins and other biomolecules. This substance is often studied in the context of membrane biology, drug delivery systems, and as a model compound for understanding lipid interactions in cellular membranes. Its unique structure allows for various applications in biochemistry and pharmacology, particularly in the development of liposomal formulations and targeted drug delivery systems.

Formula: C₃₂H₆₆NO₇P

InChI: InChI=1/C32H66NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-27-37-29-32(40-31(2)34)30-39-41(35,36)38-28-25-22-20-23-26-33(3,4)5/h32H,6-30H2,1-5H3/t32-/m1/s1

SMILES: CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCCCCCC[N+](C)(C)C)OC(=O)C

Synonyms:

• Platelet Activating Factor-16,Antagonist
• (2R)-2-(acetyloxy)-3-(octadecyloxy)propyl 6-(trimethylammonio)hexyl phosphate

U 66985

CAS: 99103-16-9

U 66985 is a Platelet-activating factor (PAF) receptor antagonist that inhibit the electrophysiological effects of PAF.

Formula: C₃₂H₆₆NO₇P

Color and Shape: Solid

Molecular weight: 607.84

Ref: TM-T68185