CAS 99156-45-3

17B-estradiol 3-glucuronide 17-*sulfate dipotassi

Description:

17B-estradiol 3-glucuronide 17-sulfate dipotassium, identified by the CAS number 99156-45-3, is a conjugated form of the hormone estradiol, which is a key estrogen in the human body. This compound is characterized by the presence of both glucuronide and sulfate moieties, which enhance its solubility and facilitate its excretion from the body. The dipotassium salt form indicates that the compound contains two potassium ions, which can influence its stability and bioavailability. Typically, such conjugated forms of hormones are less biologically active than their parent compounds, serving primarily as metabolites that are more readily eliminated. The structural modifications in 17B-estradiol 3-glucuronide 17-sulfate contribute to its pharmacokinetic properties, affecting how it interacts with estrogen receptors and its overall role in physiological processes. This compound is often studied in the context of hormone metabolism, endocrine function, and potential implications in health and disease, particularly in relation to estrogen-related conditions.

Formula: C₂₄H₃₂KO₁₁S

InChI: InChI=1/C24H32O11S.K/c1-24-9-8-14-13-5-3-12(33-23-20(27)18(25)19(26)21(34-23)22(28)29)10-11(13)2-4-15(14)16(24)6-7-17(24)35-36(30,31)32;/h3,5,10,14-21,23,25-27H,2,4,6-9H2,1H3,(H,28,29)(H,30,31,32);

SMILES: CC12CCC3c4ccc(cc4CCC3C1CCC2OS(=O)(=O)O)OC1C(C(C(C(C(=O)O)O1)O)O)O.K

Synonyms:

• Hexopyranosiduronic Acid, 17-(Sulfooxy)Estra-1,3,5(10)-Trien-3-Yl, Monopotassium Salt

β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium salt

CAS: 99156-45-3

Formula: C₂₄H₃₀O₁₁SK₂

Molecular weight: 604.75

Ref: 7W-GL5997

β-Estradiol-d3 3-(β-D-Glucuronide) 17-Sulfate Dipotassium Salt

Controlled Product

CAS: 99156-45-3

Formula: C₂₄D₃H₂₇K₂O₁₁S

Color and Shape: Neat

Molecular weight: 607.769

Ref: TR-E888092

β-Estradiol 3-(β-D-Glucuronide) 17-Sulfate Dipotassium Salt

Controlled Product

CAS: 99156-45-3

Formula: C₂₄H₃₀O₁₁S·2K

Color and Shape: Neat

Molecular weight: 604.75

Ref: TR-E888090

β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium

CAS: 99156-45-3

β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a synthetic, nonsteroidal estrogen with a high affinity for the human estrogen receptor. It is used in the treatment of various types of breast cancer and as hormone replacement therapy. β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a part of the drug class selective estrogen receptor modulators (SERMs). The compound has been shown to have antiestrogenic activity through its ability to compete with estradiol for binding to the estrogen receptor. This compound also has some antiandrogenic effects and can inhibit sex hormone binding globulin (SHBG), leading to increased levels of free testosterone in blood plasma.

Formula: C₂₄H₃₂O₁₁S•K₂

Purity: Min. 95%

Molecular weight: 606.77 g/mol

Ref: 3D-ME182700