CAS 99165-17-0

epidermin

Description:

Epidermin is a peptide antibiotic that is produced by the bacterium Staphylococcus epidermidis. It belongs to the class of compounds known as lantibiotics, which are characterized by the presence of unusual amino acids and post-translational modifications, such as lanthionine and methyllanthionine. Epidermin exhibits antimicrobial activity, particularly against Gram-positive bacteria, making it of interest in the field of pharmaceuticals for its potential use as an antibiotic. The structure of epidermin includes a cyclic framework that contributes to its stability and activity. Its mechanism of action typically involves disrupting bacterial cell wall synthesis, leading to cell lysis. Additionally, epidermin has been studied for its potential applications in treating infections, particularly those caused by antibiotic-resistant strains. Research continues to explore its properties, including its efficacy, safety, and potential therapeutic uses in various medical applications. Overall, epidermin represents a significant area of interest in the development of new antimicrobial agents.

Formula: C₉₈H₁₄₁N₂₅O₂₃S₄

Synonyms:

• PubChem ID: 16132391
• epidermin
• L-Cysteinamide, L-isoleucyl-L-alanyl-D-cysteinyl-L-lysyl-L-phenylalanyl-L-isoleucyl-L-cysteinyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-lysyl-(2Z)-2-amino-2-butenoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-[(1Z)-2-mercaptoethenyl]-, cyc...
• L-Cysteinamide,L-isoleucyl-L-alanyl-D-cysteinyl-L-lysyl-L-phenylalanyl-L-isoleucyl-L-cysteinyl-threo-3-mercapto-D-2-aminobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-lysyl-(Z)-2,3-didehydro-2-aminobutanoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-(2-mercaptoethenyl)-,cyclic (3® 7),(8® 11),(16® 21),(19® 21)-tetrakis(sulfide),(Z)-
• (Z)-L-Isoleucyl-L-alanyl-D-cysteinyl-L-lysyl-L-phenylalanyl-L-isoleucyl-L-cysteinyl-threo-3-mercapto-D-2-aminobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-lysyl-(Z)-2,3-didehydro-2-aminobutanoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-(2-mercaptoethenyl)-L-cysteinamidecyclic (3® 7),(8® 11),(16® 21),(19® 21)-tetrakis(sulfide)
• Staphylococcin 1580
• 1-Thia-4,7,10,13-tetraazacyclohexadecane,cyclic peptide deriv.
• 1H,9H-Pyrrolo[2,1-i][1,4,7,10]thiatriazacyclotridecine,cyclic peptide deriv.
• 12,19-Dithia-2,5,8,16,22,25-hexaazabicyclo[12.6.5]pentacosane,cyclic peptide deriv.

Epidermin

CAS: 99165-17-0

Epidermin is a type A lantibiotic and is a tetracyclic peptide composed of 21 amino acids, exhibiting antibiotic activity against numerous Gram-positive bacteria. Epidermin functions as both a metabolite and an antimicrobial agent.

Formula: C₉₈H₁₄₁N₂₅O₂₃S₄

Color and Shape: Solid

Molecular weight: 2165.58

Ref: TM-TN10078