CAS 99199-60-7

6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid

Description:

6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is a chemical compound characterized by its unique bicyclic structure, which includes a benzopyran moiety. This compound features a fluorine atom at the 6-position and a carboxylic acid functional group at the 2-position, contributing to its reactivity and potential biological activity. The presence of the fluorine atom can enhance lipophilicity and influence the compound's pharmacokinetic properties. The dihydrobenzopyran structure suggests that it may exhibit interesting interactions with biological targets, making it a candidate for research in medicinal chemistry. Additionally, the carboxylic acid group can participate in hydrogen bonding and ionic interactions, which may be relevant in drug design and development. Its CAS number, 99199-60-7, allows for easy identification in chemical databases. Overall, this compound's structural features suggest potential applications in pharmaceuticals, particularly in the development of novel therapeutic agents.

Formula: C₁₀H₉FO₃

InChI: InChI=1S/C10H9FO3/c11-7-2-4-8-6(5-7)1-3-9(14-8)10(12)13/h2,4-5,9H,1,3H2,(H,12,13)

InChI key: InChIKey=ZNJANLXCXMVFFI-UHFFFAOYSA-N

SMILES: C(O)(=O)C1OC=2C(=CC(F)=CC2)CC1

Synonyms:

• 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-
• 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid
• 6-Fluoro-3,4-dihydro-2H-benzopyran-2-carboxylic acid
• 6-Fluorochroman-2-carboxylic acid
• 6-fluoro-3,4-dihydro-2H-chromene-2-carboxylic acid

6-Fluorochromane-2-carboxylic acid

CAS: 99199-60-7

Formula: C₁₀H₉FO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 196.1751

Ref: IN-DA00IK8N

6-Fluorochroman-2-carboxylic acid

CAS: 99199-60-7

6-Fluorochroman-2-carboxylic acid

Purity: 98%

Molecular weight: 196.18g/mol

Ref: 54-PC903709

6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid

CAS: 99199-60-7

Color and Shape: Neat

Ref: 86-MM0947.01

6-Fluorochroman-2-carboxylic Acid

CAS: 99199-60-7

Formula: C₁₀H₉FO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 196.18

Ref: 3B-F1086

6-Fluorochromane-2-carboxylic acid

CAS: 99199-60-7

Formula: C₁₀H₉FO₃

Purity: 95%

Color and Shape: Solid, Powder

Molecular weight: 196.177

Ref: 10-F066578

rac-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic Acid

Controlled Product

CAS: 99199-60-7

Applications Nebivolol intermediate.
References Van de Water, A., et al.: J. Cardiovasc. Pharmacol., 11, 552 (1988), McNeely, W., et al.: Drugs, 57, 633 (1999), Galetta, F., et al.: Biomed. Pharmacother., 59, 15 (2005),

Formula: C₁₀H₉FO₃

Color and Shape: Neat

Molecular weight: 196.18

Ref: TR-F590990

6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid

CAS: 99199-60-7

6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is a synthetic compound that has been used in the Friedel-Crafts reaction to synthesize diastereomeric derivatives. It also shows anti-tuberculosis activity and can be used to monitor the active site of phosphatases. 6FDA has been shown to inhibit the phosphatase activity of protein tyrosine phosphatase 1B (PTP1B) and protein tyrosine phosphatase 2C (PTP2C). In addition, 6FDA inhibits the hydrogenation reduction of 3,4-dihydroisoindole phosphate (DIP) by H2 in vitro. This reaction is catalyzed by DIP reductase. The carbonyl groups on 6FDA are able to react with epoxide groups on nebivolol hydrochloride in an

Purity: Min. 95%

Ref: 3D-FF31340