Defensin HNP-2, also known as human neutrophil peptide 2, is a member of the defensin family, which are small cationic peptides known for their antimicrobial properties. It is primarily produced by neutrophils and plays a crucial role in the innate immune response. HNP-2 exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses, functioning by disrupting microbial membranes. Structurally, defensins are characterized by a conserved cysteine framework that forms disulfide bonds, contributing to their stability and function. HNP-2 is typically composed of 29 amino acids and has a net positive charge, which enhances its interaction with negatively charged microbial membranes. In addition to its antimicrobial functions, HNP-2 is involved in modulating immune responses, including chemotaxis and the activation of immune cells. Its role in inflammation and potential implications in various diseases make it a subject of interest in immunology and therapeutic research. Overall, defensin HNP-2 is a vital component of the human immune system, contributing to the first line of defense against pathogens.

defensin hnp-2

99287-07-7: Defensin HNP-2, also known as human neutrophil peptide 2, is a member of the defensin family, which are small cationic peptides known for their antimicrobial properties. It is primarily produced by neutrophils and plays a crucial role in the innate immune response. HNP-2 exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses, functioning by disrupting microbial membranes. Structurally, defensins are characterized by a conserved cysteine framework that forms disulfide bonds, contributing to their stability and function. HNP-2 is typically composed of 29 amino acids and has a net positive charge, which enhances its interaction with negatively charged microbial membranes. In addition to its antimicrobial functions, HNP-2 is involved in modulating immune responses, including chemotaxis and the activation of immune cells. Its role in inflammation and potential implications in various diseases make it a subject of interest in immunology and therapeutic research. Overall, defensin HNP-2 is a vital component of the human immune system, contributing to the first line of defense against pathogens.

<p>Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.</p>

CAS 99287-07-7

defensin hnp-2

Defensin HNP-2 human

Ref: TM-T41134

Defensin HNP-2

Ref: 7W-GL6052